Program
The Immunological Monitoring Laboratory monitors clinical trials of viral diseases, processes clinical specimens, and analyzes immune system responses. Our scientists perform cytokine analyses, determine viral loads, and quantify antigen-specific antibody levels in plasma from patients and nonhuman primates with bacterial and viral diseases.…
The Immunological Monitoring Laboratory monitors clinical trials of viral diseases, processes clinical specimens, and analyzes immune system responses.
The laboratory processes and archives blood products from patients enrolled in numerous ongoing clinical trials at the National Institutes of Health Clinical Center. This extensive archive…
Program
The Clinical Support Laboratory processes and works with samples from clinical trials at the National Cancer Institute and tests samples, with an emphasis on the immune system’s function. We work with principal investigators to study the status of the immune system in clinical trial participants or nonhuman primates who get treated with anticancer…
The Clinical Support Laboratory provides clinical trial processing support to the National Cancer Institute and performs sample testing with an emphasis on immune function.
We work with National Cancer Institute investigators on immune status of clinical trial subjects treated with anti-cancer immune modulators.
The laboratory provides…
Program
The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction.
Supporting pharmacokinetic analysis of clinical trials
The Blood Processing Core is part of…
The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction.
The core collects clinical specimens from inpatient units and clinics within the National Institutes…
Program
The Bioprocessing Laboratory integrates clinical and laboratory activities through biospecimen lifecycle management. The Bioprocessing Laboratory and Trial Logistics Support Group partners with intramural and extramural investigators to translate clinical workflows into practical specimen collection, processing, and storage procedures. These…
The Bioprocessing Laboratory integrates clinical and laboratory activities through full specimen lifecycle management.
The Bioprocessing Laboratory and Trial Logistics Support Group partners with intramural and extramural investigators to translate clinical workflows into practical specimen collection, processing, and storage procedures. These…
Program
The AIDS Monitoring Laboratory provides clinical trial support by performing sequential immune function studies in people living with HIV or other emerging/re-emerging infectious diseases as they receive treatment.
The AIDS Monitoring Laboratory provides clinical trial support by performing sequential studies of immune function in individuals with HIV or other emerging or re-emerging infectious diseases throughout the patient’s treatment.
Our work helps assess the efficacy and mode of action of investigational treatment agents and guides determination of …
Program
The Biopharmaceutical Development Program offers resources for and expertise in the development of investigational biological products that move promising treatments for cancer, rare diseases, HIV/AIDS, and other infectious diseases into clinical trials. We focus on products that are in early development, beginning with the demonstration of…
The Biopharmaceutical Development Program offers resources for and expertise in the development of investigational biological products that move promising treatments for cancer, rare diseases, AIDS, and infectious diseases into clinical trials.
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The program provides leading-edge development and analytical…
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Nondiagnostic clinical assays quantify drug mechanisms and responses in human clinical trials, including predicted biomarkers of safety and efficacy, as well as mechanistic markers of pharmacodynamics and toxicodynamics. These biospecimen assays are used to support key decisions during drug development.
The integrity of these assays is…
Program
The Cancer Immunoprevention Laboratory develops and tests novel cancer preventive agents, including vaccines, chemoprevention agents, and small molecules, in mouse models in collaboration with several extramural institutions under the sponsorship of the National Cancer Institute. The laboratory is helping develop vaccines to prevent the onset of…
The Cancer Immunoprevention Laboratory focuses on the development and preclinical evaluation of new cancer prevention vaccines and other treatments.
The laboratory evaluates the immunogenicity of novel vaccines targeted to prevent a variety of cancers including cervical, colorectal, prostate, and several solid tumors.
The team collaborates…
Program
The Vaccine, Immunity, and Cancer Directorate conducts preclinical and clinical research in the areas of vaccines, infections and cancer, with an emphasis on human papillomavirus (HPV) and SARS-CoV-2. We develop standards and assays that we validate and use in clinical studies to advance the understanding of immune responses to infection and…
The program helps inform public health decisions by providing data and analysis of antibody responses in a variety of clinical trials. Our translational science is focused on critical health concerns including cancer, HPV, and COVID-19.
Our teams evaluate and validate serology assays and provide scientific and laboratory support for the…
Program
The Clinical Monitoring Research Program facilitates strategic support of global clinical research programs conducted by the National Institutes of Health by providing comprehensive clinical trials operations and project management services from concept to cure.
Responding to urgent need for clinical trials during times of crisis
Our…
The Clinical Monitoring Research Program Directorate facilitates strategic support of clinical research programs by providing comprehensive clinical trials operations and program/project management services to support research sponsored by the National Institutes of Health. We support researchers conducting clinical research in domestic and…
