• A KRAS-specific inhibitor could be the key to attacking RAS-mutation-driven cancers, and these compounds are being optimized with the intent to develop them for clinical application.

    Targeting the "Undruggable" Oncogene

    Until recently, finding an effective RAS inhibitor seemed impossible. Today, there's hope. 

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  • A Janus G3 Automated Workstation at the Cancer Genomics Research Laboratory, one of the instruments used to conduct the TypeSeq assay.

    New Method for HPV Detection Measures Up to Leading-Edge Techniques

    HPV is a family of more than 200 sexually transmitted viruses, about 18 of which can cause cancer.

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  • Biophysical Journal, The Premier Journal of Quantitative Biology, Volume 116, Number 6, March 19, 2019, www.biophysj.org, Biophysical Society, Cell Press

    Study Defines How KRAS Gets Removed From its Active Spot

    The research may offer new ways to target unwanted cell growth, a hallmark of cancer.

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  • Ulrich Baxa, senior microscopist at the National Cryo Electron Microscopy Facility, has seen the facility grow to house two additional microscopes, including the FEI Glacios (white-and-black cabinet, left of image).

    More Than Two Years in, Cryo-EM Facility is Gaining Ground

    To date, 12 studies using structures obtained at the facility have been published.

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  • University of Delaware campus

    FNL Launches Partnership with University of Delaware

    The collaboration aims at pushing the limits of high-performance computing for cancer research.

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Who We Are Discovery, innovation, and success in the biomedical sciences. Learn More

The Frederick National Laboratory is dedicated to improving human health through discovery and innovation in the biomedical sciences, focusing on cancer, AIDS, and emerging infectious diseases.

Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public's interest.