Recent advances in cryo-EM technology have made it possible for scientists to obtain images and structures of proteins and macromolecular complexes in greater detail than ever before. This has created a surge in demand for cryo-EM experiments that has far outstripped the supply of instruments and cryo-EM trained workforce.

As demand for cryo-EM in biomedical research continues to grow, so too, does the demand for cryo-EM education and training. The Frederick National Laboratory is uniquely positioned to help address this need due to long-standing expertise in the cryo-EM domain with experienced and trained personnel as well as access to advanced instrumentation.


The Frederick National Laboratory hosted scientists seeking to learn more about cryo-electron microscopy and who anticipated using the technique in future research for the inaugural National Cryo-EM Facility Cryo-EM Training Program in Sept. 2022 in Frederick, Maryland.
Scientists gained experience in:  

  • grid preparation
  • screening and data collection
  • data processing  
  • model building and validation

All scientists at institutions with early-stage cryo-EM programs or plans to create one were encouraged to apply.

Future session

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