We offer the scientific community a wide array of services ranging from expert colony management to the development and performance of technical procedures aimed at disease induction, characterization, and treatment of animal models.
Comprehensive support to investigators
Technical development in preclinical cancer research
Our capabilities and specializations
Generation of tumor models
We generate and expand genetically engineered mouse models and induce tumors chemically or virally. Additionally, we generate subcutaneous and orthotopic tumor models using murine or human cells. We also implant patient-derived xenografts subcutaneously or into organs or tissues of animals that match the tumor histotype.
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Subcutaneous cell injections
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Orthotopic cell injections (intracardial, intramuscular, intraperitoneal, intravenous)
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Surgical cell injections (intra-cisternal, intra-femoral, intra-renal, intra-cranial, mamary fat pad, intra-thoracic, intra-hepatic) and tissue implants (subcutaneous, intra-renal, intra-cecal)
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Viral instillations (intra-nasal, intra-tracheal, intra-vaginal, intra-buccal)
Treatment modalities
We administer investigational compounds via medicated water, customized diets, topical skin painting, or injections.
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Treatment compounds delivered by several routes, including drinking water, specialized diets, and topical skin applications
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Therapeutic compounds also delivered by multiple routes of injections
Localized tumor treatments
We use state-of-the-art equipment and techniques, including irradiators that allow localized tumor treatments.
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Whole-body X-ray irradiation
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Localized X-ray irradiation