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Clinical Research

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Victor Ssempijja remembers there being many fatherless households in his hometown in Uganda during his childhood. In fact, he says he could count the number of complete families on just his fingers. The other fathers had died of HIV and associated complications. “I actually grew up thinking that men were not supposed to live long,” he said…
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The antiviral treatment remdesivir accelerated recovery time among hospitalized participants with advanced COVID-19 compared to participants who received placebo containing inactive ingredients, according to results of a clinical trial published May 22 in the New England Journal of Medicine. The median time to recovery was 11 days for…
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In its urgent efforts to confront the novel coronavirus, the U.S. Food and Drug Administration (FDA) has tapped the Frederick National Laboratory for Cancer Research (FNL) to scientifically inform its decision-making on potential approval of blood tests for the presence of antibodies to SARS-CoV-2. FNL has an adaptive cancer research…
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A team from the Frederick National Laboratory’s Biopharmaceutical Development Program is developing a new autologous cell therapy line that uses engineered chimeric antigen receptor (CAR) T cells to treat acute myeloid leukemia, a particularly aggressive form of pediatric blood cancer. This foray into cell immunotherapy represents a new avenue of…