The Applied and Developmental Research Directorate provides essential clinical and biological monitoring, regulatory support, biospecimen processing and storage, assay development, and regulatory and project management support to the National Cancer Institute and the clinical programs within the National Institute of Allergy and Infectious Diseases. 

Supporting clinical research

We support the intramural and extramural communities through clinical and laboratory monitoring of clinical trials, regulatory support, and biospecimen storage.  

Providing dedicated services

Collaboration Opportunities

We have services available to researchers within the National Institutes of Health. To request our services, you can either go through NAS or CREX. These are ONLY for NIH researchers. To inquire about publicly accessible services, reach out to the Partnership Development Office.

Scan of patient with colorectal liver metastases
Researcher Resource

Discover the Cancer Imaging Archive

Our scientists oversee the Cancer Imaging Archive, which hosts a large archive of de-identified medical images of cancer accessible for public download.
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Clinical Services Program

Laboratories within the Clinical Services Program provide dedicated support to the clinical trials at the National Cancer Institute, including the Division of Cancer Epidemiology and Genetics, the Center for Cancer Research, and the Division of Cancer Prevention. We also support clinical programs at the National Institute of Allergy and Infectious Diseases.  

Our support extends to preclinical and translational research. Several of our laboratories provide shared services that can be accessed by other institutes within the National Institutes of Health through the NCI at Frederick Accessioning System.  

The Clinical Services Program laboratories have also provided support to other government agencies through the Economy Act. 

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Wild type human prostate cells from an organoid
Biological materials repositories managed by ADRD
Several of our teams manage repositories available to investigators as part of a larger collaborative effort.
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NCI Division for Cancer Treatment and Diagnosis Support

The DCTD support group provides program-dedicated research and support, laboratory management, and administrative support to clinical, basic and translational investigations within the NCI Division of Cancer Treatment and Diagnosis. Our laboratories provide program-dedicated research and support, laboratory management, and administrative support to clinical, basic, and translational investigations within NCI's Division of Cancer Treatment and Diagnosis's scientific portfolio. Activities are focused on developing novel diagnostics and therapies for cancer.