Scientists and clinicians whose discoveries have shaped the understanding of HIV disease will provide updates on the...
There are many paths for women to travel to find success in science. That was a crucial theme conveyed by the four...
Frederick National Laboratory researchers identified a vitamin A derivative (retinoid) that when combined with a...

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More Than Two Years in, National Cryo-EM Facility is Gaining Ground

National Cryo-Electron Microscopy FacilityPosted 10/7/2019
FREDERICK, Md. -- Ulrich Baxa, Ph.D., and his team are helping to move a microscope the size of a minivan. The behemoth, a Titan Krios, is making the 29-mile trek from a Gaithersburg, Maryland, laboratory to its new home at the Frederick National Laboratory for Cancer Research. It’s a highly-sensitive, $7 million device being relocated across a greater metropolitan area…

New Partnership with University of Delaware Aims at Pushing the Limits of High-Performance Computing for Cancer Research

Posted 9/10/2019
FREDERICK, Md. -- High-performance computing and other data science technologies are enabling critical inroads in cancer research. However, bringing together the necessary computing and cancer biology expertise to effectively leverage these technologies is a challenge—a challenge that a new partnership between the Frederick National Laboratory for Cancer Research and the…

Treatment Manufactured at FNL Proves Promising in Ebola Clinical Study While FNL Research Teams Advance the Trial Behind the Scenes

Clinical Monitoring Research Program, Vaccine Clinical Materials ProgramPosted 9/2/2019
Just 48 hours after an Ebola clinical trial in the Democratic Republic of Congo (DRC) was stopped early because two therapies appeared to significantly reduce patients’ fatality rates, two Frederick National Laboratory staff members boarded a plane to help with the next step. Meanwhile, the national laboratory’s Vaccine Clinical Materials Program (VCMP) sent a shipment of…

Frederick National Laboratory and Purdue University Establish Biomedical Research Collaboration

Posted 8/27/2019
FREDERICK, Md. – Frederick National Laboratory for Cancer Research has launched a partnership with Purdue University that aims to enhance and accelerate research initiatives, technological innovation, and workforce development in the biomedical sciences. The two-year memorandum of understanding between Frederick National Laboratory (FNL) and Purdue University Center for…

FNL and Mexican Cancer Institutes Initiate Scientific and Training Exchange

Posted 8/14/2019
MEXICO CITY -- An engagement between the Frederick National Laboratory for Cancer Research and the National Cancer Institute of Mexico (INCan) kicked off in July with a presentation about the FNL to a gathering of Mexican cancer researchers in Mexico City. FNL Chief Science Officer Leonard Freedman, Ph.D. highlighted some of the national laboratory’s key initiatives in a…

Scientists Use Cryo-Electron Microscope to Catch CRISPR-Cas9 Gene Editing in Action

Posted 8/12/2019
FREDERICK, Md. -- CRISPR is one of the most widely used technologies in the nascent quest to edit the human genome, and the precision “instrument” that makes it so effective is Cas9, a programmable enzyme harnessed from bacterial cells that cuts DNA strands at specific targets and replaces one gene with another. In a July 8 paper published in Nature Structural and Molecular…

Frederick National Laboratory’s Partnership with Moffitt and Weill Cornell Advances HPV Vaccine Research

Posted 7/25/2019
FREDERICK, Md. -- Ligia Pinto, Ph.D., sees science as a way to change lives and help people in need—and that is precisely what a study recently co-authored by her team at the Frederick National Laboratory for Cancer Research and collaborators at the H. Lee Moffitt Cancer Center and Research Institute and Weill Cornell Medicine holds promise to do. According to the paper,…

Published Studies Show Breadth of HIV Research and Discovery at Frederick National Laboratory

AIDS and Cancer Virus Program, Basic Science ProgramPosted 7/22/2019
FREDERICK, Md. -- Recent scientific papers co-authored by researchers at the Frederick National Laboratory for Cancer Research present novel discoveries about HIV and one similar infection from three fields of inquiry about the virus, all with the potential to further discoveries leading to prevention or treatment of HIV infection. The papers reveal a deeper understanding…

Cancer Biologists Get Expert Perspective on Research Potential of Imaging Technologies

Posted 7/2/2019
FREDERICK, Md. – Leading experts in the imaging science and cancer biology field convened at Hood College June 21-23 for an in-depth look at the potential of new imaging technologies to transform their work. The Imaging Science and Cancer Biology Symposium, sponsored by Hood College and Leidos Biomedical Research, Inc. featured presentations exploring advances in understanding…

Patient Eligibility for Pediatric Precision Medicine Trial Doubles Estimates

Molecular Characterization LaboratoryPosted 6/27/2019
The National Cancer Institute–Children’s Oncology Group trial known as Pediatric MATCH (Molecular Analysis for Therapy Choice) trial launched in 2017, with significant operations and technical support from the Frederick National Laboratory for Cancer Research. Focusing on patients aged 1–21, Pediatric MATCH seeks to determine whether precision medicines that are designed to…