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      New cancer data commons expands available clinical and translational data

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      FNL GCREM

      New training series for rapid response clinical research available for free

      Virtual training series aims to educate and empower clinical researchers to perform rapid response clinical studies in atypical environments.
    KRAS G12C

    RAS drug discovery at Frederick National Laboratory reaches lung cancer patients in a clinical trial

    A first-in-human study seeks to determine the drug’s safety and tolerability and to detect potential antitumor activity.
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      Newsletter

      Summer 2024 SeroNews

      Latest edition of SeroNews highlights viral evolution.
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      Importance of innovation Within FNL, innovation plays a pivotal role in delivering new and enhanced technologies that empower us to tackle essential scientific inquiries, enhance our services, and ultimately contribute to the wellbeing of patients.
      Vladimir Popov, Ph.D., MBA
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      High Fidelity Dec 9, 2024

      How Much Should I Trust NGS Data: A View from Regulatory Science

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    RAS Initiative Symposium 2024

    Progress against RAS-driven cancers lauded at RAS Symposium, with more candidate treatments on the horizon

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      Download files to demultiplex next-generation sequencing and determine the abundance of individually barcoded SIV/SHIV viral lineages.
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      Assay Cascade Characterization Program

      Next deadline to apply: March 3, 2025

      Preclinical characterization of nanoparticles to facilitate the regulatory review of nanotechnology concepts intended as cancer therapies and diagnostics.
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      Researcher Resource

      New training for rapid response clinical research

      Learn about challenges in clinical research during emergency infectious disease outbreaks and strategies to overcome them.
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        • An in vitro drug release study in human plasma
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        • Detection of Mycobacterium tuberculosis DNA
      Did you know?
      We are home to unique scientific expertise and technological capabilities available nowhere else. The Technical Services Program through the Partnership Development Office makes some of these capabilities and services readily available to the external research community at-cost to advance biomedical research around the world.
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      FNL Initiative

      Scientific Standards Hub

      Collection of scientific groups at FNL working to develop, deposit and share standards and references in biological research.
    Apply Now-Feb. 14

    Cancer Reagent Target Requests

    Interested researchers with readily available protein/peptides can submit a request for antibody generation.
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      2024 Tech Showcase

      Technology Showcase team blends new and old approaches for 2024 event

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      FNL Patents

      Virtual training series aims to educate and empower clinical researchers to perform rapid response clinical studies in atypical environments.
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      Blanket Purchase Agreement for Biologicals
      Closed 1 week 3 days ago (11/22/2024)
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      B25132
    Register Your Interest

    Become a Vendor

    Potential vendors seeking to work with us must first complete a New Vendor Registration.
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    What do you enjoy about working at the Frederick National Laboratory? I enjoy coming to work every day because of the wonderful team we have.
    Chris Karlovich, Ph.D.
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    Did you know?
    In the 10-year period 2012-2022, the Vaccine Clinical Materials Program completed 300+ shipments supporting approximately 100 clinical trials across 45 products.

Simone Difilippantonio

Director, Animal Research Technical Support
Director, Gnotobiotics Facility
difilips@mail.nih.gov
Frederick National Laboratory logo Frederick National Laboratory for Cancer Research is operated by Leidos Biomedical Research, Inc. for the National Cancer Institute.
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  • Research
    • Science Areas
      • AIDS and Cancer Virus Program
        • Sections
          • Retroviral Evolution Section
          • Retroviral Pathogenesis Section
          • Retrovirus-Cell Interaction Section
          • Viral Oncology Section
          • Viral Persistence Section
        • Cores
          • Biological Products Core
          • Cellular Immunity Core
          • HIV Molecular Monitoring Core
          • Nonhuman Primate Research Support Core
          • Quantitative Molecular Diagnostics Core
          • Tissue Analysis and Retroviral Protein Chemistry Core
          • Viral Evolution Core
      • Basic Science Program
        • Computational Structural Biology Section
        • Epigenetics Section
        • HLA Immunogenetics Section
        • Molecular Immunology Section
      • Bioinformatics and Computational Science
        • Advanced Biomedical Computational Science
        • Center for Technical Operations Support
      • Cancer Research Technology Program
        • Advanced Cryo-Electron Microscopy Technology Group
        • Antibody Characterization Laboratory
        • Cancer Data Science Initiatives
        • CLIA Molecular Diagnostics Laboratory
        • Imaging Mass Cytometry Laboratory
        • Protein Expression Laboratory
      • Laboratory Animal Sciences Program
        • Animal Diagnostics Laboratory
        • Animal Research Technical Support
        • Center for Advanced Preclinical Research
        • Genome Modification Core
        • Gnotobiotics Facility
        • Laboratory Animal Medicine
        • Molecular Histopathology Laboratory
        • Mouse Modeling and Cryopreservation
        • Small Animal Imaging Program
      • Vaccine, Immunity, and Cancer Directorate
        • Cancer Immunoprevention Laboratory
        • Center of Excellence for Serology Development and Emergency Preparedness
        • HPV and COVID-19 Serology Laboratories
        • SeroNet Coordinating Center
    • Clinical Trial Support
      • Applied and Developmental Research Directorate
        • Clinical Services Program
          • AIDS Monitoring Laboratory
          • Bioprocessing Laboratory
          • Blood Processing Core
          • Clinical Support Laboratory
          • Flow Cytometry Support Laboratory
          • Immunological Monitoring Laboratory
          • Laboratory of Human Retrovirology and Immunoinformatics
          • Laboratory of Molecular Cell Biology
          • Neutrophil Monitoring Laboratory
          • Radiochemistry Program
          • Virus Isolation and Serology Laboratory
        • DCTD Support
          • Cancer Imaging Informatics Laboratory
          • Clinical Pharmacodynamics - Biomarkers Program
          • In Vitro Evaluation and Molecular Pharmacology Laboratories
          • In Vivo Evaluation Program
          • Investigative Toxicology Laboratory
          • NExT Chemical Biology Consortium Support Programs
          • Natural Products Support Group
          • Pharmacokinetics and Drug Analysis Group
          • Radiochemistry Support Group
      • Biopharmaceutical Development Program
      • Clinical Monitoring Research Program
      • Clinical Research Directorate
        • Biospecimen Research Group
        • Cancer Genomics Research Laboratory
        • Drug Discovery and Development Program
        • Molecular Characterization Laboratory
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  • Stable Clone Production for Anti-CD6 Monoclonal Antibodies
  • Stable Clone Production for Anti-CD6 Monoclonal Antibodies