Biomedical Imaging

Supporting research to connect cancer phenotypes to genotypes.

Morehouse joins the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC).

Scientists presented innovative imaging techniques and discussed how they are leveraging them to advance cancer research.

On any given day, microscopist Susan Lea, D.Phil., and her team at NCI at Frederick collect more data than can fit on any standard hard drive, creating a challenge for data storage and analysis. Their average data collection is 5 terabytes, a quantity roughly 20 times the storage capacity of a 256-gigabyte laptop or the equivalent of storing…

The Frederick National Laboratory will host a new training program in Frederick, Maryland, September 12-16 for cancer researchers who want to build expertise in cryo-electron microscopy (cryo-EM). Cryo-EM is a microscopy technique where samples are flash-frozen and bombarded with electrons to generate images. The resulting high-resolution…

Frederick National Laboratory (FNL) scientists, led by Stephan Stern, Ph.D., and their colleagues have created a novel imaging agent that, with further development, might detect deadly pancreatic cancer at its earliest, most-treatable stages and thereby improve the prognosis for patients. Pancreatic cancer has a high mortality rate because it…

Pilot study suggests a near real-time method of imaging prostate cancer to aid in organ-sparing treatments.

The spike protein critical for coronavirus research -- and for some COVID-19 vaccines -- slowly deteriorates while in storage, which can affect research results and vaccine production, a new study suggests. But the effect can be reversed. The SARS-CoV-2 spike protein, which is used in laboratories around the world, is unstable under…

Meta tags are used on web pages. Metadata is added to photographs. Both help people find, use, and reuse these digital assets. Scientists say the same is needed for image data in biology, and urgently so. “A single imaging data set could be a thousand images,” said Frederick National Laboratory imaging scientist Kedar Narayan. “Someone might…

A data set doesn’t sound like a flashy scientific advance, but that impression belies a concept with the potential to enable eye-catching science. Such is the case with CEM500K, a new data set created by Kedar Narayan, Ph.D., and Ryan Conrad in the Center for Molecular Microscopy at Frederick National Laboratory. As reported in eLife last week…