Biomedical Imaging

The Cancer Imaging Archive, managed by FNL's Cancer Imaging Informatics Laboratory, supports a research community that seeks to connect cancer phenotypes to genotypes. To accomplish this, the archive hosts data sets that connect clinical images with patient genomic data and proteomic data. The archive is part of National Cancer Institute…

A national effort to understand the molecular basis of numerous cancers by analyzing proteins and genes will benefit from greater diversity in patient samples through a new agreement with the Morehouse School of Medicine, a historically Black medical school in Atlanta. MSM joins the National Cancer Institute’s Clinical Proteomic Tumor…

Three scientists from the region presented innovative imaging techniques and discussed how they are leveraging them to advance cancer research and ultimately improve human health at the Biotech Connector seminar on Wednesday, May 17, the second in this year’s series sponsored by the Frederick National Laboratory for Cancer Research and the…

On any given day, microscopist Susan Lea, D.Phil., and her team at NCI at Frederick collect more data than can fit on any standard hard drive, creating a challenge for data storage and analysis. Their average data collection is 5 terabytes, a quantity roughly 20 times the storage capacity of a 256-gigabyte laptop or the equivalent of storing…

The Frederick National Laboratory will host a new training program in Frederick, Maryland, September 12-16 for cancer researchers who want to build expertise in cryo-electron microscopy (cryo-EM). Cryo-EM is a microscopy technique where samples are flash-frozen and bombarded with electrons to generate images. The resulting high-resolution…

Frederick National Laboratory (FNL) scientists, led by Stephan Stern, Ph.D., and their colleagues have created a novel imaging agent that, with further development, might detect deadly pancreatic cancer at its earliest, most-treatable stages and thereby improve the prognosis for patients. Pancreatic cancer has a high mortality rate because it…

A pilot study suggests a near real-time method of imaging prostate cancer to aid in organ-sparing treatments, and an innovative as well as accurate way to see whether the cancer has spread. These dual findings stem from research reported in Molecular Imaging and Biology on a relatively new radiotracer used in dynamic positron emission…

The spike protein critical for coronavirus research -- and for some COVID-19 vaccines -- slowly deteriorates while in storage, which can affect research results and vaccine production, a new study suggests. But the effect can be reversed. The SARS-CoV-2 spike protein, which is used in laboratories around the world, is unstable under…

Meta tags are used on web pages. Metadata is added to photographs. Both help people find, use, and reuse these digital assets. Scientists say the same is needed for image data in biology, and urgently so. “A single imaging data set could be a thousand images,” said Frederick National Laboratory imaging scientist Kedar Narayan. “Someone might…

The Radiochemistry Support Group develops radiochemical methods to produce radiotracers for in vivo imaging in HIV studies, as well as chemical and biochemical methods to synthesize, identify, and characterize radiolabeled antibody, cytokine, and small-molecule probes.