The Laboratory Animal Sciences Program (LASP) is a comprehensive resource for scientists performing animal-based research to gain a better understanding of cancer, HIV/AIDS, and other infectious diseases.
The program provides an integrated portfolio of research animal programs, including the development of genetically engineered mouse models, cryopreservation and assisted reproduction, pathology and histotechnology, small animal imaging, molecular diagnostics, and animal husbandry. LASP provides the highest possible quality of animal care and assists investigators in the use of healthy animals appropriate for their research objectives.
LASP provides oversight of animal research facilities by guarding against the accidental introduction of pathogens in experiments, administers accurate clinical diagnosis and preoperative care, and offers quality animal holding facilities and related services. These include the quarantine of imported animals, rederivation of pathogen-carrying strains, and the comprehensive monitoring of the health status of animal research colonies.
- Exploring the effects of nicotine in human prostate cancer cells and prostate cancer-prone TRAMP mice
- Mass spectometry-based metabolomics identifies longitudinal urinary metabolite profiles predictive of radiation-induced cancer
- Findings warrant caution against a systemic inhibition of microRNA-155 (miR-155) for anticancer therapy
- New animal model could boost research on AIDS drugs and vaccines
Program Areas and Laboratories
- Small Animal Imaging Program (SAIP)
- Gnotobiotics Program
- Animal Research Technology
- NCI Mouse Repository
- Pathology/Histotechnology Laboratory (PHL)
- Molecular Imaging Laboratory (MIL)
- High-Throughput Animal Genotyping Laboratory (HTAGL)
- Animal Molecular Diagnostics Laboratory (AMDL)