Available Strain Details

Strain Information
Common Strain Name: SWR Brca2 exon 27 del Pricing and Ordering Information
Strain Nomenclature: SWR.129P2(Cg)-Brca2tm1Kamc/Nci
Animal State: Frozen Embryo
Release Category (Required for MTA form): A

Strain Description: A viable Brca2 germline knockout (with exon 27 alone deleted) that is highly susceptible to a wide range of tumors is placed on a pure inbred background (SWR).
Mutation Information
Mutation Type: Targeted
Gene Name: Breast cancer 2
Gene Symbol: Brca2
Transgene Name:
Transgene Symbol:
Promotor Name:
Promotor Symbol:
Current Genetic Background: SWR.129P2
Approx. Generation: 17
Organ Site: Breast
Additional Information
Cryopreservation Mating Scheme: The cryopreservation mating scheme is wildtype SWR females x heterozygous males. When maintained as a live colony, breeder pairs were distributed as heterozygotes.
Genotyping Information: Protocol 1: Allele: Brca2<tm1Kamc>
Protocol 2: Allele: Brca2<tm1Kamc>
Donating Investigator: Dr. Kimberly McAllister

Key Reference: UNPUBLISHED