Virus Isolation and Serology Laboratory

The Virus Isolation and Serology Laboratory performs virus detection and quantification, sample genotyping, and sequential serology tracking studies for the National Institute of Allergy and Infectious Diseases. We carry out serologic and molecular testing to monitor treatment and natural history trials for HIV, SARS-CoV-2, influenza virus, and new and reemerging pathogens. During the recent COVID-19 Pandemic, the laboratory’s contributions resulted in over 15 publications in leading scientific journals.

Our team supports clinical trials conducted at the National Institute of Allergy and Infectious Diseases and with NIAID collaborators. Our studies provide information for the next stages of research and advance ongoing drug efficacy and epidemiology studies for NIAID’s Laboratory of Immunoregulation.

Our laboratory has evolved from the early days of HIV-focused research, when cultures and syncytia surveys were mainstay techniques, to a facility that supports a wider range of investigative activities and utilizes today’s cutting-edge molecular research tools, including real-time polymerase chain reaction and next-generation sequencing. We pivoted to collaborating in studies that developed cures for hepatitis C and treatments for influenza and SARS-CoV-2 infections. We continue to explore new and better ways to support our clients at the National Institutes of Health and their collaborators around the world.