Frederick National Laboratory Part of SC19 “Best Paper” Team

A multidisciplinary team including members of the Frederick National Laboratory has been recognized with the “Best Paper” award at SC19, a prestigious international conference for high-performance computing, networking, storage, and analysis. Of the 344 papers submitted to SC19, only 87 were accepted, and just one was named Best Paper.

Biophysical Journal, The Premier Journal of Quantitative Biology, Volume 116, Number 6, March 19, 2019,, Biophysical Society, Cell Press

FREDERICK, Md. -- A study defining how an oncogenic protein gets removed from its active spot may offer new ways to target unwanted cell growth, a hallmark of cancer.

KRAS is a membrane-binding protein that functions as a molecular switch to regulate cellular activity, and is the most frequently mutated oncogene in human cancer. Normal KRAS controls cell growth. When KRAS is mutated, the signal is disrupted and cells grow continuously.