Scientists and clinicians whose discoveries have shaped the understanding of HIV disease will provide updates on the...
There are many paths for women to travel to find success in science. That was a crucial theme conveyed by the four...
Frederick National Laboratory researchers identified a vitamin A derivative (retinoid) that when combined with a...

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Biopharmaceutical Program Fills Critical Niche at the Forefront of Cancer Research

Biopharmaceutical Development ProgramPosted 10/3/2018
FREDERICK, Md. -- The development of a modified poliovirus to treat glioblastoma, a deadly form of brain cancer, is one of the latest examples of the Frederick National Laboratory for Cancer Research stepping in to fill a critical need that few others could meet with developing and manufacturing novel biological agents for early-phase clinical trials. During a Phase I…

Frederick National Laboratory Builds Upon Collaborations in Computational Science

Posted 9/24/2018
FREDERICK, Md. -- Eric Stahlberg, Ph.D., has been named director of Biomedical Informatics and Data Science (BIDS) at the Frederick National Laboratory for Cancer Research in a move that will amplify his role in building partnerships in high-performance computing and data science in cancer research. There was an exceptional slate of candidates for this position, reflecting the…

Frederick National Laboratory Takes Cancer Research into Space

Posted 9/17/2018
FREDERICK, Md. -- The Frederick National Laboratory for Cancer Research is taking its science to new heights – with an experiment rocketing into orbit around the Earth. The aim is to grow protein crystals in the weightlessness of space where, beyond the full influence of Earth’s gravity, they might proliferate more easily and become larger and more perfect than those…

New Technical Service Makes HPV Genotyping Available to More Researchers

Posted 8/30/2018
Note: As of 4/25/23, this service is temporarily unavailable as the team works to validate a new version. FREDERICK, Md. -- A new chemical test available through the Frederick National Laboratory for Cancer Research could accelerate human papillomavirus (HPV) research by detecting 40 percent more HPVs than the current gold standard research test. There are upwards of…

Fennessey and Colleagues Take a Prize in the Technical Publications Competition

Posted 8/12/2018
Christine Fennessey, Ph.D., scientist I and manager of the Viral Evolution Core, AIDS and Cancer Virus Program, has received one of the awards in the 2018 Leidos Technical Publications Competition for a paper describing a novel method for studying simian immunodeficiency virus. The paper, which won a prize in the “Life Sciences & Medicine” category, was one of…

Study Provides Insight into Establishment of Persistent AIDS Virus Infection; Highlights Potential Viral Vulnerability

Posted 8/6/2018
FREDERICK, Md. -- A new study led by investigators from the Frederick National Laboratory for Cancer Research in collaboration with colleagues from the Oregon Health and Science University (OHSU) utilizing a nonhuman primate model infected with Simian Immunodeficiency Virus (SIV) could have significant implications for future research into the prevention and potential cure of…

Study Provides Insight into Establishment of Persistent AIDS Virus Infection

Posted 8/6/2018
A new study led by investigators from the Frederick National Laboratory for Cancer Research in collaboration with colleagues from the Oregon Health and Science University (OHSU) utilizing a nonhuman primate model infected with Simian Immunodeficiency Virus (SIV) could have significant implications for future research into the prevention and potential cure of Human…

FNL leads interdisciplinary approach to study RAS-driven cancers

Posted 7/24/2018
Nearly one-third of all human cancers are driven by mutations in RAS genes, including almost all pancreatic cancers. Treating these cancers has puzzled scientists for decades, and many RAS proteins are considered virtually undruggable. The Frederick National Laboratory for Cancer Research is attacking this longstanding problem from several new vantage points. It’s leading…

Frederick National Laboratory Leads Interdisciplinary Approach to Study RAS-Driven Cancers

Posted 7/23/2018
FREDERICK, Md. -- Nearly one-third of all human cancers are driven by mutations in RAS genes, including almost all pancreatic cancers. Treating these cancers has puzzled scientists for decades, and many RAS proteins are considered virtually undruggable. The Frederick National Laboratory for Cancer Research is attacking this longstanding problem from several new vantage…

Frederick National Laboratory Leads Study to Understand Immune Response to Nanoparticles

Nanotechnology Characterization LaboratoryPosted 7/11/2018
FREDERICK, Md. -- The Frederick National Laboratory for Cancer Research is opening potential new avenues for coaxing the human immune system to fight cancer and other diseases through microscopic particles, or nanoparticles. The use of nanoparticles to transport drugs to cancer cells is a growing field that has piqued scientists’ interest over the last two decades.…