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      SIV

      Study offers guidance for targeting HIV’s viral reservoir

      New research from the AIDS and Cancer Virus Program employed a novel nonhuman primate model using a barcoded virus that allows detailed tracking and dynamics of the biology of the RCVR.
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      The Cancer Imaging Archive

      Demographically diverse images are sought for national cancer resource

      Arrow Icon

    Newly identified antibodies block many influenza strains in laboratory tests

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  • Innovation & Initiatives
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      Newsletter

      Summer 2024 SeroNews

      Latest edition of SeroNews highlights viral evolution.
    • Innovation
      • Center for Innovation and Strategic Partnerships
      • Patents
      Importance of innovation Within FNL, innovation plays a pivotal role in delivering new and enhanced technologies that empower us to tackle essential scientific inquiries, enhance our services, and ultimately contribute to the wellbeing of patients.
      Vladimir Popov, Ph.D., MBA
    • Scientific Series
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      Life Sciences Symposium Sep 23-25, 2024

      HIV in 2024: Progress, Problems & Prospects

      Hood College-FNL cohosted conference.
    KRAS

    RAS Initiative study shines the spotlight on less-understood KRAS4a

    A four-year effort revealed new information about a less-studied KRAS variant.
  • Investigator Resources
    • Data & Repositories
      • BRB Preclinical Biologics Repository
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      SIV/SHIV

      Barcode Analysis Tool

      Download files to demultiplex next-generation sequencing and determine the abundance of individually barcoded SIV/SHIV viral lineages.
    • Training & Education
      • cGMP Training
      • FNL Global Clinical Research Educational Modules
      • NCEF Cryo-EM Training Program
      Researcher Resource

      New training for rapid response clinical research

      Learn about challenges in clinical research during emergency infectious disease outbreaks and strategies to overcome them.
    • Technical Services
      • Program Overview
      • HIV/SIV Services
        • Cellular or Tissue SIV/SHIV RNA and DNA testing
        • HIV/SIV Single Genome Amplification and Sequencing
        • Lineage-specific Next Gen Multiplex In Situ Hybridization for HIV or SIV RNA and DNA
        • Next-generation sequencing analysis of barcoded SIV, SHIV, or HIV
        • Novel CD4+ T Cell Specific Immunohistochemistry Detection and Analysis
        • Plasma or CSF SIV/SHIV RNA measurements
        • Quantitative Assessment of Lymphoid Tissue Fibrosis
        • Quantitative assessment of HIV or SIV viral DNA in laser capture microdissected immune cells
        • Viral Integration Site Analysis (VISA) for HIV studies
      • Laboratory Animal Services
        • Assessment of Drug Efficacy in a Survival Study
        • In Vitro Cell Cytotoxicity Evaluation
        • Pharmacokinetic Evaluation in Kras/p53 PDAC Mice
        • Time Course Assessment of Tumor Response to Therapeutics
        • Tolerance Evaluation of Experimental Compound in Kras/p53 PDAC Mice
        • Use of Mouse Embryonic Stem Cells Expressing miRNAs
      • Nanomedicine & Nanoformulation
        • An in vitro drug release study in human plasma
        • Pharmacokinetic study of nanomedicine in rats
      • Other
        • Detection of Mycobacterium tuberculosis DNA
      Researcher Resource

      Nanotechnology Characterization Laboratory

      Comprehensive preclinical characterization of nanomedicine formulations.
    • Universal Standards & Reference Materials
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      FNL Initiative

      Scientific Standards Hub

      Collection of scientific groups at FNL working to develop, deposit and share standards and references in biological research.
    Researcher Resource

    National Cryo-Electron Microscopy Facility

    High-resolution imaging for U.S. extramural cancer researchers.
  • Work With Us
    • Collaboration
      • Partnership Development Office
      • Partnership Mechanisms
      • Academic Partnerships
      Panelists & exhibitor

      FNL joins two panels at 2024 BIO International Convention

      Our Center for Innovation & Strategic Partnerships will be part of panels and exhibiting at BIO.
    • Tech Transfer & Licensing
      • Intellectual Property and Strategic Agreements
      NCI & FNL event Sep 4, 2024

      2024 Technology Showcase

      Technology presentations, poster sessions, and expert discussions on topics including financing, leveraging incubators and working with patient advocacy groups.
    • Vendors & Subcontractors
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        • (DMID) NextGen COVID-19 Vaccines - Fill & Finish - A Platform Trial to Evaluate Next Generation COVID-19 Vaccines.
        • BPA FOR SAFETY EYE GLASSES
        • SERVICE MAINTENANCE AGREEMENT FOR REVVITY IMAGING SYSTEMS
        • SERVICE MAINTENANCE AGREEMENT FOR WATERS UHPLC SYSTEM
        • Service & Maintenance Agreement for NMR Spectrometer
        • Service & Maintenance Agreement for Spectrometers
        • Service Maintenance Agreement for 1ea Sequencing System
      • Contracts and Acquisitions
      • Small Businesses, Nonprofits & HBCUs
      solicitation
      Stable Clone Production for Anti-CD6 Monoclonal Antibodies
      Due in 2 weeks (09/23/2024)
      Research & Development Services & Subcontracts
      S24-058
    Register Your Interest

    Become a Vendor

    Potential vendors seeking to work with us must first complete a New Vendor Registration.
  • Careers
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    • Internships and Fellowships

    Upcoming Career Fairs

    09/13 @ 10:00amLeavey Center Georgetown University Annual Fall Career Fair 09/24 @ 11:00amAdele H. Stamp Student Union University of Maryland STEM Career Fair
  • About FNL
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    Did you know?
    To date, the In Vitro Evaluation and Molecular Pharmacology Laboratories 300,000+ pure compounds and biologics and 34,000+ crude natural product extracts have been tested against the NCI 60-cell-line panel.

Lyuba Khavrutskii

Partnership Development Lead, Partnership Development Office
Portrait photo
Frederick National Laboratory logo Frederick National Laboratory for Cancer Research is operated by Leidos Biomedical Research, Inc. for the National Cancer Institute.
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  • Research
    • Science Areas
      • AIDS and Cancer Virus Program
        • Sections
          • Retroviral Evolution Section
          • Retroviral Pathogenesis Section
          • Retrovirus-Cell Interaction Section
          • Viral Oncology Section
          • Viral Persistence Section
        • Cores
          • Biological Products Core
          • Cellular Immunity Core
          • HIV Molecular Monitoring Core
          • Nonhuman Primate Research Support Core
          • Quantitative Molecular Diagnostics Core
          • Tissue Analysis and Retroviral Protein Chemistry Core
          • Viral Evolution Core
      • Basic Science Program
        • Computational Structural Biology Section
        • Epigenetics Section
        • HLA Immunogenetics Section
        • Molecular Immunology Section
      • Bioinformatics and Computational Science
        • Advanced Biomedical Computational Science
        • Center for Technical Operations Support
      • Cancer Research Technology Program
        • Advanced Cryo-Electron Microscopy Technology Group
        • Antibody Characterization Laboratory
        • Cancer Data Science Initiatives
        • CLIA Molecular Diagnostics Laboratory
        • Imaging Mass Cytometry Laboratory
        • Nanotechnology Characterization Laboratory
        • National Cryo-Electron Microscopy Facility
        • Protein Expression Laboratory
      • Laboratory Animal Sciences Program
        • Animal Diagnostics Laboratory
        • Animal Research Technical Support
        • Center for Advanced Preclinical Research
        • Genome Modification Core
        • Gnotobiotics Facility
        • Laboratory Animal Medicine
        • Molecular Histopathology Laboratory
        • Mouse Modeling and Cryopreservation
        • Small Animal Imaging Program
      • Vaccine, Immunity, and Cancer Directorate
        • Cancer Immunoprevention Laboratory
        • Center of Excellence for Serology Development and Emergency Preparedness
        • HPV and COVID-19 Serology Laboratories
        • SeroNet Coordinating Center
    • Clinical Trial Support
      • Applied and Developmental Research Directorate
        • Clinical Services Program
          • AIDS Monitoring Laboratory
          • Bioprocessing Laboratory
          • Blood Processing Core
          • Clinical Support Laboratory
          • Flow Cytometry Support Laboratory
          • Immunological Monitoring Laboratory
          • Laboratory of Human Retrovirology and Immunoinformatics
          • Laboratory of Molecular Cell Biology
          • Neutrophil Monitoring Laboratory
          • Radiochemistry Program
          • Virus Isolation and Serology Laboratory
        • DCTD Support
          • Cancer Imaging Informatics Laboratory
          • Clinical Pharmacodynamics - Biomarkers Program
          • In Vitro Evaluation and Molecular Pharmacology Laboratories
          • In Vivo Evaluation Program
          • Investigative Toxicology Laboratory
          • NExT Chemical Biology Consortium Support Programs
          • Natural Products Support Group
          • Pharmacokinetics and Drug Analysis Group
          • Radiochemistry Support Group
      • Biopharmaceutical Development Program
      • Clinical Monitoring Research Program
      • Clinical Research Directorate
        • Biospecimen Research Group
        • Cancer Genomics Research Laboratory
        • Drug Discovery and Development Program
        • Molecular Characterization Laboratory
      • Vaccine Clinical Materials Program
  • Innovation & Initiatives
    • Initiatives
      • RAS Initiative
      • Scientific Standards Hub
      • SeroNet
    • Innovation
      • Center for Innovation and Strategic Partnerships
      • Patents
    • Scientific Series
      • Biotech Connector
      • High Fidelity
      • Life Sciences Symposium
      • RAS Initiative Symposium
      • Scientific Partners Distinguished Lecture Series
      • Technology Showcase
      • Women in Science Speak
  • Careers
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    • Benefits
    • Diversity and Inclusion
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  • About
    • Who We Are
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  • Service & Maintenance Agreement for Environmental Test Chambers
  • Service & Maintenance Agreement for Microbial Detection System
  • Service Maintenance Agreement for De-Rouging, Passivation, Cleaning of WFI & Clean Steam Systems
  • Stable Clone Production for Anti-CD6 Monoclonal Antibodies
  • Stable Clone Production for Anti-CD6 Monoclonal Antibodies