Program
The Basic Science Program conducts independent research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. The program’s areas of focus include cancer, retrovirology, basic and structural biology, informatics cellular mechanisms, and the genetic factors that influence disease.
A focus on…
The Basic Science Program conducts independent research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics.
Our goal is to understand biological processes related to cancer and other diseases and to develop cutting-edge tools to accelerate scientific progress.
The program’s areas of focus…
Program
The Radiochemistry Support Group develops radiochemical methods to produce radiotracers for in vivo imaging in HIV studies, as well as chemical and biochemical methods to synthesize, identify, and characterize radiolabeled antibody, cytokine, and small-molecule probes.
The Radiochemistry Support Group develops radiochemical methods to produce radiotracers for in vivo imaging in HIV studies, and chemical and biochemical methods to synthesize, identify, and characterize the radiolabeled antibody, cytokine, and small molecular probes.
We develop radiotracers to support noninvasive, in-vivo whole-body imaging in…
Program
The Laboratory of Molecular Cell Biology conducts research in collaboration with scientists at the National Institute of Allergy and Infectious Diseases to understand the biology of T-cell activation and HIV persistence.
We support the Laboratory of Immunoregulation by developing and performing quantitative and qualitative polymerase chain…
The Laboratory of Molecular Cell Biology conducts research in collaboration with scientists at the National Institute of Allergy and Infectious Diseases to understand the biology of T cell activation and HIV persistence.
We support the Laboratory of Immunoregulation by developing and performing quantitative and qualitative polymerase chain…
Program
The Laboratory of Human Retrovirology and Immunoinformatics conducts basic and clinical research to better understand the immunopathological effects of infectious diseases and how those effects are influenced by genetics.
Basic and translational research group
We support and collaborate with National Institute of Allergy and Infectious…
The Laboratory of Human Retrovirology and Immunoinformatics performs basic, clinical, and bioinformatic research to gain a better understanding of the immunopathological effects of HIV and HIV-related infectious diseases and how they’re influenced by genetics. We support and collaborate with the National Institute of Allergy and Infectious…
Program
The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction.
Supporting pharmacokinetic analysis of clinical trials
The Blood Processing Core is part of…
The Blood Processing Core monitors viral load in patients with HIV and performs sequential studies using samples obtained from patients with cancer, AIDS, chronic granulomatous disease, or other diseases associated with immunologic dysfunction.
The core collects clinical specimens from inpatient units and clinics within the National Institutes…
Program
The AIDS Monitoring Laboratory provides clinical trial support by performing sequential immune function studies in people living with HIV or other emerging/re-emerging infectious diseases as they receive treatment.
The AIDS Monitoring Laboratory provides clinical trial support by performing sequential studies of immune function in individuals with HIV or other emerging or re-emerging infectious diseases throughout the patient’s treatment.
Our work helps assess the efficacy and mode of action of investigational treatment agents and guides determination of …
Program
The Viral Persistence Section seeks to better understand the establishment, maintenance, and consequences of persistent AIDS virus infections.
To achieve these goals, we employ existing and novel nonhuman primate (NHP) models of HIV infection and our extensive experience in the administration and evaluation of antiretroviral agents in NHPs.…
The Viral Persistence Section studies the establishment, spread, and maintenance of persistent AIDS virus infections and persistent opportunistic viral infections that cause cancer in the setting of AIDS.
The laboratory uses a combination of nonhuman primate models of HIV infection, along with advanced cell culture, virology, and molecular…
Program
The Viral Oncology Section studies the epidemiology, immune response, and genetics of Kaposi sarcoma–associated herpesvirus (KSHV). Our work extends to related oncogenic viruses and associated malignancies.
Understanding the role of viruses in cancer
Seven viruses are known to cause about 20% of human cancers. Our studies are primarily…
The Viral Oncology Section studies the role of viruses in cancer, focusing primarily on Kaposi’s sarcoma–associated herpesvirus (KSHV) and related malignancies. Our research encompasses epidemiology, molecular virology, immunology, and translational studies.
Program
The Viral Evolution Core was established in 2009 with a mission to provide expertise in specialized sequencing techniques, molecular cloning, and viral evolution analyses to support the AIDS and Cancer Virus Program, National Cancer Institute, National Institutes of Health, and extramural investigators in conducting a broad range of AIDS-research…
The Viral Evolution Core provides expertise in specialized sequencing techniques, molecular cloning, and viral evolution analyses. The core primarily generates viral genome sequencing data and analysis. Our scientists support the AIDS and Cancer Virus Program, National Cancer Institute, National Institutes of Health, and the broader AIDS research…
Program
The Tissue Analysis and Retroviral Protein Chemistry Core provides state-of-the-art tissue analysis capabilities, including immunofluorescence, single- and multi-label immunohistochemistry, singleplex and multiplex in situ hybridization, ultra-high-plex spatial stain, quantitative image analysis, laser-capture microdissection, antibody conjugation…
The Tissue Analysis Core provides state-of-the-art tissue analysis capabilities including immunofluorescence, single and double label immunohistochemistry, in situ hybridization, quantitative image analysis, and laser capture microdissection. The core supports investigators within the AIDS and Cancer Virus Program and both intramural and…
