Request for Information/Sources Sought - Manufacture of Hydroxocobalamin

Sources Sought
Person of Contact Bernadette Davis (bernadette.davis@nih.gov)
Proposal Due Date Monday, May 18, 2026 (Due in 12 hours 38 minutes)
NAICS Codes 541715, 541714
  • Research Category Research & Development Services & Subcontracts
  • Solicitation Number S26-XX50
  • NCI OA Contract Number 75N91019D00024 – NCI-FFRDC

Description

The Frederick National Laboratory for Cancer Research (FNLCR), a Federally Funded Research and Development Center (FFRDC), currently operated by Leidos Biomedical Research, Inc. (Leidos Biomed) for the National Cancer Institute, is seeking information regarding manufacturing of hydroxocobalamin.

The goal of this project is to support the cGMP manufacture of injectable hydroxocobalamin for Phase I Clinical Use, to include assay validation, feasibility, cGMP manufacturing and stability.

As part of this Request for Information, the following information is being requested:

• A Rough-Order-of-Magnitude (ROM) estimate of the above elements inclusive of labor, services fees, materials and supplies, other pass-through costs, and any other costs needed to complete the requested tasks.

• Projected timelines and anticipated period of performance to complete the tasks outlined above.


This Request for Information (RFI) is for INFORMATIONAL PURPOSES ONLY and SHALL NOT be construed as a solicitation or as an obligation on the part of Leidos Biomedical Research, Inc. (Leidos Biomed). All information received will be handled as Proprietary Information. Based on responses, a formal Request for Proposal (RFP) may be issued.

Proposal Instructions

For a copy of the abbreviated scope of objectives, please contact Ms. Bernadette Davis at bernadette.davis@nih.gov

Specific questions about this RFI are due by 3:00 PM ET, on Thursday, May 7, 2026.

RFI Responses due date has been extended from 3:00 PM ET, on Wednesday, May 13, 2026 to 3:00 PM ET on Monday, May 18, 2026.

Modified By Date Modified Sort ascending Comment
Shaneeka Owens

S26-XX50 Amendment No. 1 was issued on May 12, 2026 issuing RFI questions and responses.  Additionally, the response due date has been extended to 3:00pm (EST) on Monday, May 18, 2026.