Immunology

Study subject showed complications in antiretroviral therapy efficacy from inflammation and secondary infections.

A growing body of evidence suggests that a single dose of vaccine against cancer-causing human papilloma virus (HPV) may protect as well as the standard two-or-more dose regimen. This would make it easier to protect more women, especially in low-income areas where vaccine access is scarce. A study published recently in The Lancet Global Health…

A new test detects exposure to viruses that cause COVID-19 and their relatives. Research using it could aid efforts to protect against infections.    A team at the Frederick National Laboratory for Cancer Research developed a test capable of assessing exposure to the virus that causes COVID-19 and to a selection of its variants and viral…

Five new projects led by Frederick National Laboratory for Cancer Research (FNL) scientists have earned Laboratory Directed Exploratory Research (LDER) funding for the upcoming fiscal year. The LDER program, which was modeled after the U.S. Department of Energy’s Laboratory Directed Research and Development program, provides FNL scientists…

Natural immune response may point to possible cure for others.

Results showed no correlation between severity of symptoms and levels of antibodies.

Presence of HLA-A*03 appears to impede immune checkpoint inhibition therapy across tumor types.

The National Institutes of Health (NIH) awarded three Frederick National Laboratory teams with NIH Director’s Awards for innovative approaches to COVID-19-related research that advances knowledge and enhances health. “It is a tremendous honor for three Frederick National Laboratory teams to be nominated by three distinct entities within NIH…

Frederick National Laboratory for Cancer Research (FNL) plays a central role in a public-private network that has kept scores of substandard COVID-19 blood antibody tests out of circulation and helped ensure that marketed tests give accurate results. This critical pandemic response is detailed in a scientific study published January 12 in…

The coronavirus pandemic was heating up and so was the urgent need for blood tests to confirm infections. It was spring 2020, and a host of companies were developing and submitting newly minted tests to the Food and Drug Administration (FDA) for potential Emergency Use Authorization (EUA) approval. The FDA had to know if the tests were…