Content tagged as

Immunology

News
Frederick National Laboratory scientists were part of a multi-institutional collaboration that has identified a second patient whose natural immune response to HIV infection appears to have cured her of the disease, raising the question: Can this be replicated? Only three other patients have ever been declared fully cured, but each of these…
Program
Image The COVID-19 Serology Laboratory establishes standards and coordinates research for the National Cancer Institute Serological Sciences Network (SeroNet).   At the start of the COVID-19 pandemic in March, 2020, our scientists pivoted to evaluate the performance of SARS-CoV-2 antibody tests for the U.S.…
News
You may have had a sore arm, felt tired, or had a headache. Maybe you ran a slight fever. You might have heard these things happen because your COVID-19 shot is working as it should. On the other hand, a lack of side-effects does not point to vaccine failure, according to a new study. The relationship between a reaction to COVID-19 vaccines and…
News
Scientists have identified a genetic variant that can predict whether immunotherapy drugs called immune checkpoint inhibitors, used to treat cancer, might fail in certain patients. The team’s findings, which appear in Lancet Oncology, point to HLA-A*03, an allele (a form of a gene) found on chromosome 6 of human DNA. The presence of HLA-A*03 in…
News
The National Institutes of Health (NIH) awarded three Frederick National Laboratory teams with NIH Director’s Awards for innovative approaches to COVID-19-related research that advances knowledge and enhances health. “It is a tremendous honor for three Frederick National Laboratory teams to be nominated by three distinct entities within NIH…
Basic page
SeroNews is the quarterly newsletter from the NCI Serological Sciences Network. Each edition includes clinical and translational serology highlights. This newsletter will be published every three to four months and is intended to summarize key priorities, perspectives, and events of a very engaged and enthusiastic team of scientists, clinicians…
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Frederick National Laboratory for Cancer Research (FNL) plays a central role in a public-private network that has kept scores of substandard COVID-19 blood antibody tests out of circulation and helped ensure that marketed tests give accurate results. This critical pandemic response is detailed in a scientific study published January 12 in…
News
The coronavirus pandemic was heating up and so was the urgent need for blood tests to confirm infections. It was spring 2020, and a host of companies were developing and submitting newly minted tests to the Food and Drug Administration (FDA) for potential Emergency Use Authorization (EUA) approval. The FDA had to know if the tests were…
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A study conducted in part by researchers of the Frederick National Laboratory for Cancer Research (FNL) HPV Serology Laboratory showed middle-aged men who received three doses of the quadrivalent human papillomavirus (HPV) vaccine experienced a robust immune response to vaccine antigens—critical for long-term protection against HPV. The…
News
Predicting disease severity from a SARS-CoV-2 infection has been an elusive but critical need in addressing the COVID-19 pandemic, as some patients experience mild symptoms while others develop fatal complications. As scientists try to determine what contributes to infection levels and mortality, several medical signs are providing potential…