Content tagged as

Immunology

The Molecular Immunology Section studies mechanisms of gene regulation, focusing on the innate immune system. The section is affiliated with, and provides expertise in gene regulation to the Laboratory of Cancer Immunometabolism of the National Cancer Institute Center for Cancer Research. 
The HLA Immunogenetics section studies the influence of immunogenetic variation on risk of human disease, outcome to therapeutic treatment, and vaccination.  These studies include elucidation of the functional basis for the genetic associations identified.  The human leukocyte antigen (HLA) class I and class II genetic loci are the main subjects …
The Basic Science Program conducts independent research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics.  Our goal is to understand biological processes related to cancer and other diseases and to develop cutting-edge tools to accelerate scientific progress.  The program’s areas of focus…
The Virus Isolation and Serology Laboratory performs sequential serologic, virus detection and quantification, and genotyping studies for the National Institute of Allergy and Infectious Diseases.   The results of these studies provide information to further research and support ongoing drug efficacy and epidemiology studies.   The Virus…
The Laboratory of Molecular Cell Biology conducts research in collaboration with scientists at the National Institute of Allergy and Infectious Diseases to understand the biology of T cell activation and HIV persistence.  We support the Laboratory of Immunoregulation by developing and performing quantitative and qualitative polymerase chain…
The Laboratory of Human Retrovirology and Immunoinformatics performs basic, clinical, and bioinformatic research to gain a better understanding of the immunopathological effects of HIV and HIV-related infectious diseases and how they’re influenced by genetics. We support and collaborate with the National Institute of Allergy and Infectious…
The Immunological Monitoring Laboratory monitors clinical trials of viral diseases, processes clinical specimens, and analyzes immune system responses.  The laboratory processes and archives blood products from patients enrolled in numerous ongoing clinical trials at the National Institutes of Health Clinical Center. This extensive archive…
The Clinical Support Laboratory provides clinical trial processing support to the National Cancer Institute and performs sample testing with an emphasis on immune function.  We work with National Cancer Institute investigators on immune status of clinical trial subjects treated with anti-cancer immune modulators.    The laboratory provides…
The Viral Persistence Section studies the establishment, spread, and maintenance of persistent AIDS virus infections and persistent opportunistic viral infections that cause cancer in the setting of AIDS.  The laboratory uses a combination of nonhuman primate models of HIV infection, along with advanced cell culture, virology, and molecular…
The Viral Oncology Section studies the role of viruses in cancer, focusing primarily on Kaposi’s sarcoma–associated herpesvirus (KSHV) and related malignancies. Our research encompasses epidemiology, molecular virology, immunology, and translational studies.