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Research Technology

News
The National Cancer Institute and Frederick National Laboratory for Cancer Research will hold the annual Technology Showcase on Wednesday, Sept. 7 in a hybrid format to welcome in-person attendees as well as remote participants from around the United States and the world. The event is scheduled from noon to 5:30 pm ET at the FNL’s Advanced…
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Pursuing future partners and better weather, the Frederick National Laboratory for Cancer Research (FNL) recently attended the BIO 2022 International Convention in San Diego. This convention is one of the largest biotech partnering events internationally, with over 3,000 foreign and domestic companies represented at this year’s week-long June…
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The success of today’s COVID-19 vaccines has given medical nanotechnology a long-awaited boost, with a renewed interest in its potential for treating disease among big pharma and small start-ups. Over the years, nanotechnology has had its ups and downs in the public eye, cycling from peaks of excitement and fanfare–and a little too much hype–…
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On any given day, microscopist Susan Lea, D.Phil., and her team at NCI at Frederick collect more data than can fit on any standard hard drive, creating a challenge for data storage and analysis. Their average data collection is 5 terabytes, a quantity roughly 20 times the storage capacity of a 256-gigabyte laptop or the equivalent of storing…
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An initiative at Frederick National Laboratory for Cancer Research (FNL) is confronting what’s been dubbed the scientific “reproducibility crisis.” The effort, called STAR TREC (the Standards References and Training Research Committee), seeks to help the scientific community address reproducibility issues and aims to spur dialogue about better…
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The National Institutes of Health (NIH) awarded three Frederick National Laboratory teams with NIH Director’s Awards for innovative approaches to COVID-19-related research that advances knowledge and enhances health. “It is a tremendous honor for three Frederick National Laboratory teams to be nominated by three distinct entities within NIH…
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Think of a tumor and you might envision a disorganized mass. But tumors can also form a thin sheet over a surface. These can be hard to treat, especially when the surface has wrinkles and crevices. But there may be a new approach. Solid tumors can be successfully removed with surgery and residual cells destroyed. But cancers like the asbestos-…
Program
The Protein Expression Laboratory generates DNA, cell line, and protein reagents for biomedical research from basic science to drug discovery. The team uses cutting-edge protein production technologies to generate proteins using bacteria, insect cells, or mammalian cells at scales from micrograms to grams. Quality control is a major emphasis of…
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The Frederick National Laboratory for Cancer Research (FNL) not only tackles some of the world’s greatest biomedical challenges but also serves as a shared national resource to enable high-quality research beyond its walls. One way FNL does this is through the Technical Services Program. The Technical Services Program gives investigators…
Program
Image The Advanced Cryo-Electron Microscopy Technology Group explores emerging imaging platforms and develops methodologies, focusing on projects with the potential to make cryo-EM a more widely accessible technique.  The team focuses on single-particle analysis and cryo-electron tomography. Our group aims to…