Event
The Frederick National Laboratory for Cancer Research together with the Frederick County Chamber of Commerce organizes the quarterly Biotech Connector Speaker Series. This event promotes and supports the Frederick County and surrounding areas’ biotech and bioscience community and provides an inside look at local advances.
Please join fellow…
News
The Biopharmaceutical Development Program (BDP) has entered a new area of investigational cancer treatment development: an Antibody-Drug Conjugate (ADC).
The research is a collaboration of the Frederick National Laboratory for Cancer Research (FNL) and the Dana-Farber Cancer Institute with funding provided by the National Cancer Institute’s…
Basic page
The Biopharmaceutical Development Program has created cGMP training slides with information on various topics relating to cGMP. We continue to update and add to this resource.
Slide decks
Basic page
The Biopharmaceutical Development Program has developed standard operating procedures for various elements and components of the biopharmaceutical development process. Tap into our library of more than 300 standard operating procedures on topics ranging from facilities best practices to quality assurance and much more.
Search or select topics…
News
A multi-site clinical trial is in progress for lentiviral-vector-based CD33 CAR T-cell treatments for pediatric Acute Myeloid Leukemia (AML). Six sites were approved for this trial sponsored by the National Marrow Donor Program. NCI’s Division of Cancer Treatment and Diagnosis (DCTD) is funding the Biopharmaceutical Development Program to serve as…
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Naturally developing cancers in animals can be used as models for human cancer treatment. The Biopharmaceutical Development Program successfully produced multiple antibodies for immuno-oncology targets for clinical trials. More antibodies are in the discovery stage.
Dogs spontaneously develop cancers that resemble human malignancies. These…
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NCI-MATCH, one of the largest cancer precision medicine clinical trials to date, closed in 2023 and its follow-on studies will use a similar model to test combinations of treatments, evaluating a patient’s immune system prior to pairing the patient with immunotherapy against their cancer.
The Molecular Analysis for Therapy Choice (NCI-MATCH)…
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Plants, marine invertebrates, and microbes have been a major source of novel drugs against cancer, viruses, and fungal diseases. New isolation methods are making it faster and easier to discover these natural products.
To encourage ongoing drug development from natural products, a collaboration of government and contractor scientists…
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A growing body of evidence suggests that a single dose of vaccine against cancer-causing human papilloma virus (HPV) may protect as well as the standard two-or-more dose regimen. This would make it easier to protect more women, especially in low-income areas where vaccine access is scarce.
A study published recently in The Lancet Global Health…
News
A research collaboration has made early progress toward a potential vaccine for type 1 diabetes, a long-sought goal for an autoimmune disease that affects more than 1.5 million Americans.
The team, including Frederick National Laboratory computational scientist David Bell, previously discovered a new protein antibody in type 1 diabetes…
