News
A new test detects exposure to viruses that cause COVID-19 and their relatives. Research using it could aid efforts to protect against infections.
A team at the Frederick National Laboratory for Cancer Research developed a test capable of assessing exposure to the virus that causes COVID-19 and to a selection of its variants and viral…
News
Frederick National Laboratory (FNL) scientists, led by Stephan Stern, Ph.D., and their colleagues have created a novel imaging agent that, with further development, might detect deadly pancreatic cancer at its earliest, most-treatable stages and thereby improve the prognosis for patients.
Pancreatic cancer has a high mortality rate because it…
Program
The Basic Science Program conducts independent research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. The program’s areas of focus include cancer, retrovirology, basic and structural biology, informatics cellular mechanisms, and the genetic factors that influence disease.
A focus on…
The Basic Science Program conducts independent research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics.
Our goal is to understand biological processes related to cancer and other diseases and to develop cutting-edge tools to accelerate scientific progress.
The program’s areas of focus…
Program
The Laboratory of Human Retrovirology and Immunoinformatics conducts basic and clinical research to better understand the immunopathological effects of infectious diseases and how those effects are influenced by genetics.
Basic and translational research group
We support and collaborate with National Institute of Allergy and Infectious…
The Laboratory of Human Retrovirology and Immunoinformatics performs basic, clinical, and bioinformatic research to gain a better understanding of the immunopathological effects of HIV and HIV-related infectious diseases and how they’re influenced by genetics. We support and collaborate with the National Institute of Allergy and Infectious…
Program
The Viral Oncology Section studies the epidemiology, immune response, and genetics of Kaposi sarcoma–associated herpesvirus (KSHV). Our work extends to related oncogenic viruses and associated malignancies.
Understanding the role of viruses in cancer
Seven viruses are known to cause about 20% of human cancers. Our studies are primarily…
The Viral Oncology Section studies the role of viruses in cancer, focusing primarily on Kaposi’s sarcoma–associated herpesvirus (KSHV) and related malignancies. Our research encompasses epidemiology, molecular virology, immunology, and translational studies.
Program
The Tissue Analysis and Retroviral Protein Chemistry Core provides state-of-the-art tissue analysis capabilities, including immunofluorescence, single- and multi-label immunohistochemistry, singleplex and multiplex in situ hybridization, ultra-high-plex spatial stain, quantitative image analysis, laser-capture microdissection, antibody conjugation…
The Tissue Analysis Core provides state-of-the-art tissue analysis capabilities including immunofluorescence, single and double label immunohistochemistry, in situ hybridization, quantitative image analysis, and laser capture microdissection. The core supports investigators within the AIDS and Cancer Virus Program and both intramural and…
Program
The Retroviral Pathogenesis Section conducts basic, applied, and translational research to understand retroviral disease mechanisms. We work with nonhuman primate (NHP) models, employing in vitro and in vivo approaches, and evaluate strategies to more effectively prevent and treat AIDS virus infections and their consequences.
Our basic studies…
The Retroviral Pathogenesis Section conducts both in vitro and in vivo research to improve the basic understanding of AIDS virus pathogenesis through applied and basic studies. Applied studies evaluate candidate vaccines and other prevention approaches, along with studies of novel drug and immunotherapeutic interventions to target virus that…
Program
The Laboratory Animal Sciences Program is a comprehensive resource for scientists performing animal-based research to better understand cancer, HIV/AIDS, and other infectious diseases. We provide veterinary care, regulatory support, and routine and specialized husbandry services.
Our staff operates National Cancer Institute animal facilities in…
The Laboratory Animal Sciences Program is a comprehensive resource for scientists performing animal-based research to better understand cancer, HIV/AIDS, and other infectious diseases. We provide veterinary care, regulatory support, and routine and specialized husbandry services.
Image…
News
Kidney disease researchers should be on the lookout for a newly described mouse virus that appears to be relatively common and could affect the reproducibility of research involving mice that are infected but show no symptoms, according to a new study.
“Turns out, this virus is common in wild mice and research colonies around the world and…
