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The COVID-19 Serology Laboratory establishes standards and coordinates research for the National Cancer Institute Serological Sciences Network (SeroNet).
At the start of the COVID-19 pandemic in March, 2020, our scientists pivoted to evaluate the performance of SARS-CoV-2 antibody tests for the U.S.…
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The National Institutes of Health (NIH) awarded three Frederick National Laboratory teams with NIH Director’s Awards for innovative approaches to COVID-19-related research that advances knowledge and enhances health.
“It is a tremendous honor for three Frederick National Laboratory teams to be nominated by three distinct entities within NIH…
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In the push to find treatments for the novel coronavirus, a Frederick National Laboratory team helped enroll thousands of participants in clinical trials and brought on board community hospitals as new study sites to join the research effort amid the pandemic.
The partnership with community-based hospitals as clinical trial sites was…
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A grim statistic is driving Steven Rosenberg’s mission to find new cancer treatments—and his partnership with Frederick National Laboratory (FNL) to do so.
“Every year in the United States, about 600,000 people die of cancer, 90% of whom die of the solid epithelial cancers,” said Rosenberg, the M.D., Ph.D., chief of the National Cancer…
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Since its inception, the Biopharmaceutical Development Program has manufactured more than 250 lots of 100 different biopharmaceuticals to support human clinical studies, including:
Proteins and peptides
Recombinant proteins
Monoclonal antibodies (murine/humanized/chimeric)
Immunotoxins
Cytokines
Immunocytokines
Nucleic acids…
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The Virus Isolation and Serology Laboratory performs sequential serologic, virus detection and quantification, and genotyping studies for the National Institute of Allergy and Infectious Diseases.
The results of these studies provide information to further research and support ongoing drug efficacy and epidemiology studies.
The Virus…
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The Neutrophil Monitoring Laboratory performs testing to assess neutrophil dysfunction in patients with various primary immunodeficiencies.
We develop state-of-the-art assays to evaluate a variety of neutrophil functions such as reactive oxygen species production, chemotaxis, cell shape change and spreading, exocytosis, and alterations in…
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The Immunological Monitoring Laboratory monitors clinical trials of viral diseases, processes clinical specimens, and analyzes immune system responses.
The laboratory processes and archives blood products from patients enrolled in numerous ongoing clinical trials at the National Institutes of Health Clinical Center. This extensive archive…
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The Flow Cytometry Support Laboratory is a clinical laboratory that provides state-of-the-art diagnostic clinical flow cytometric testing and immunophenotyping.
We support the National Cancer Institute Flow Cytometry Laboratory in the Laboratory of Pathology. The majority of flow cytometric testing we perform involves detecting minimal residual…
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The Clinical Support Laboratory provides clinical trial processing support to the National Cancer Institute and performs sample testing with an emphasis on immune function.
We work with National Cancer Institute investigators on immune status of clinical trial subjects treated with anti-cancer immune modulators.
The laboratory provides…
