News
People with HIV on long-term antiretroviral therapy show signs of brain damage and cognitive impairment on a battery of imaging, laboratory, and functional tests, and they report a greater degree of difficulty with the routine tasks of everyday life, according to a new study.
The study, published in April in the journal Neurology, is the first…
News
Each year, the Frederick National Laboratory offers its scientists an opportunity to compete for funding to conduct the research they view as critical to advance biomedical research but is outside the scope of their daily research activities.
This year, three proposals earned funding through the program, known as the Laboratory Directed…
News
Five new projects led by Frederick National Laboratory for Cancer Research (FNL) scientists have earned Laboratory Directed Exploratory Research (LDER) funding for the upcoming fiscal year.
The LDER program, which was modeled after the U.S. Department of Energy’s Laboratory Directed Research and Development program, provides FNL scientists…
News
Frederick National Laboratory scientists were part of a multi-institutional collaboration that has identified a second patient whose natural immune response to HIV infection appears to have cured her of the disease, raising the question: Can this be replicated?
Only three other patients have ever been declared fully cured, but each of these…
News
HIV plays a direct role in causing blood cell cancers in rare instances, says a new study of HIV and tumor DNA.
Scientists have long known that HIV contributes to several cancers by weakening the immune system’s ability to fend off cancer-causing infections like Kaposi sarcoma–associated herpesvirus and Epstein-Barr virus. However, this latest…
News
The Frederick National Laboratory for Cancer Research (FNL) not only tackles some of the world’s greatest biomedical challenges but also serves as a shared national resource to enable high-quality research beyond its walls. One way FNL does this is through the Technical Services Program.
The Technical Services Program gives investigators…
Program
The Basic Science Program conducts independent research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics.
Our goal is to understand biological processes related to cancer and other diseases and to develop cutting-edge tools to accelerate scientific progress.
The program’s areas of focus…
Program
The Radiochemistry Support Group develops radiochemical methods to produce radiotracers for in vivo imaging in HIV studies, and chemical and biochemical methods to synthesize, identify, and characterize the radiolabeled antibody, cytokine, and small molecular probes.
We develop radiotracers to support noninvasive, in-vivo whole-body imaging in…
Program
The Laboratory of Molecular Cell Biology conducts research in collaboration with scientists at the National Institute of Allergy and Infectious Diseases to understand the biology of T cell activation and HIV persistence.
We support the Laboratory of Immunoregulation by developing and performing quantitative and qualitative polymerase chain…
Program
The Laboratory of Human Retrovirology and Immunoinformatics performs basic, clinical, and bioinformatic research to gain a better understanding of the immunopathological effects of HIV and HIV-related infectious diseases and how they’re influenced by genetics. We support and collaborate with the National Institute of Allergy and Infectious…
