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Virology

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Viral Evolution Core

Program
Cutting-edge sequence-based viral analysis to determine evolution, dynamics, and characterization of AIDS viruses.
The Viral Evolution Core provides expertise in specialized sequencing techniques, molecular cloning, and viral evolution analyses. The core primarily generates viral genome sequencing data and analysis. Our scientists support the AIDS and Cancer Virus Program, National Cancer Institute, National…

Retrovirus-Cell Interaction Section

Program
In vitro and in vivo approaches to study cellular immune control of AIDS viruses.
The Retrovirus-Cell Interaction Section uses both in vitro and in vivo studies to define the characteristics and potential of cellular immune control of AIDS virus infection. Our researchers study the interactions between AIDS viruses and their host cells, focusing on SIV and rhesus macaque T cell…

Retroviral Pathogenesis Section

Program
Basic, applied, and translational research to understand retroviral disease mechanism.
The Retroviral Pathogenesis Section conducts both in vitro and in vivo research to improve the basic understanding of AIDS virus pathogenesis through applied and basic studies. Applied studies evaluate candidate vaccines and other prevention approaches, along with studies of novel drug and…
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Retroviral Evolution Section

Program
Novel viral systems to leverage the advantages of nonhuman primate models.
The Retroviral Evolution Section conducts groundbreaking research to better understand fundamental features of HIV transmission, persistence, and evolution that allow the pathogen to continue evading eradication strategies. Our scientists harness molecular biology approaches to generate, manipulate, and employ novel viral…
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Quantitative Molecular Diagnostics Core

Program
Novel assays to measure AIDS virus nucleic acids and related analytes in specimens from nonhuman primate studies.
The Quantitative Molecular Diagnostics Core provides quantitative molecular analyses for laboratories within the AIDS and Cancer Virus Program, National Institutes of Health, and external research community.The core performs testing for SIV and related viruses, with a focus on …
ACVP system used to purify monoclonal antibodies and cytokines

AIDS and Cancer Virus Program

Program
The AIDS and Cancer Virus Program investigates ways to diagnose, prevent, and treat HIV infection and AIDS-related tumors associated with cancer viruses, such as Kaposi sarcoma–associated herpesvirus. We have principal investigator-headed research sections and research support cores that provide innovative, often unique, capabilities in support of…
The AIDS and Cancer Virus Program works to improve the prevention, diagnosis, and treatment of HIV infection and AIDS-related tumors through basic, applied, and translational research, including development and sharing of novel experimental models, reagents and analytical methods. Through investigator-…
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