Available Strain Details

Strain Information
Common Strain Name: CAG-LSL-EGFR-WT Pricing and Ordering Information
Strain Nomenclature: STOCK Col1a1tm1(CAG-EGFR)Char/Nci
Animal State: Cryoarchived Strains
Release Category (Required for MTA form): B3,D

Strain Description: None until presented to tissue specific Cre recombinase.
Mutation Information
Mutation Type: Targeted
Gene Name: Wild type epidermal growth factor receptor
Gene Symbol: EGFR
Transgene Name:
Transgene Symbol:
Promotor Name: CAGGS (chicken and viral)
Promotor Symbol: CAGGS
Current Genetic Background: STOCK
Approx. Generation: 7
Organ Site: Any
Additional Information
Cryopreservation Mating Scheme: The cryopreservation mating scheme is FVB females x heterozygous males. When maintained as a live colony, breeder pairs were distributed as a heterozygote (male or female) x wildtype FVB (male or female). Average litter size is 7.
Genotyping Information: Protocol 1: Allele: Col1a1<tm1(CAG-EGFR)Char>
Donating Investigator: Dr. Alain Charest

Key Reference: Zhu et al., Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2712-6. PMID: 19196966 [PubMed - indexed for MEDLINE]PMCID: PMC2650331 [Pubmed Abstract]

Sponsor: National Institutes of Health U54 CA119349, U01 CA141556