There are many laboratories within the Frederick National Laboratory for Cancer Research that have services available to the public. Our laboratories span basic, translational, and clinical science with a focus on cancer, AIDS, and infectious disease. View some of our laboratory pages below, and check back here for updates as more are added.
AIDS and Cancer Virus Program (ACVP) Laboratories
ACVP consists of five independent but highly interactive research sections headed by principal investigators, whose work spans from fundamental molecular virology through in vitro studies, to in vivo studies in non-human primate (NHP) models, to international viral epidemiology. ACVP also includes Research Support Core Groups (Cores) that provide critical and often unique technical support capabilities to ACVP laboratories and other laboratories within the NCI and NIH, and to extramural investigators.
HPV Serology Laboratory
Protection against Human Papillomavirus (HPV) infection after vaccination is believed to be mediated by HPV-specific antibodies. Antibody responses in HPV prophylactic vaccine trials have been assessed using different methods.The lack of standardized assays, procedures, and reagents accessible to the scientific community has precluded the comparison of different studies evaluating immunogenicity of HPV vaccines. The HPV Serology Laboratory at the Frederick National Laboratory was established in January 2017 to address some of these needs and advance HPV assay standardization.
The CLIA Molecular Diagnostics Laboratory (CMDL), located at the Frederick National Laboratory’s Advanced Technology Research Facility, consists of five staff members. The lab has three long-term standing projects: Affymetrix DMET microarray gene expression, PCR and DNA sequencing-based genetic mutation detection, and a Technical Service Agreement with the Lymphoma/Leukemia Molecular Profiling Project, Nanostring and CTEP.
The Frederick National Laboratory is home to the National Cryo-Electron Microscopy Facility (NCEF), a user facility to provide cancer researchers access to the latest technology for high resolution imaging with minimal delay between request for access and data collection.