The HPV and COVID-19 Serology Laboratories lead serology standardization efforts that have resulted in standard operating procedures available to the scientific community.

Standardization efforts

HPV Serology

The HPV Serology Laboratory leads an HPV Serology Standardization initiative in collaboration with the National Cancer Institute and the Bill and Melinda Gates Foundation. We invite you to download and use the following standard operating procedures in your own serology laboratory.

Protection against Human Papillomavirus (HPV) infection after vaccination is believed to be mediated by HPV-specific antibodies. Antibody responses in HPV prophylactic vaccine trials have been assessed using different methods.

The lack of standardized assays, procedures, and reagents accessible to the scientific community has precluded the comparison of different studies evaluating immunogenicity of HPV vaccines. The HPV Serology Laboratory was established to address some of these needs and advance HPV assay standardization. 

COVID-19 Serology

The COVID-19 Serology Laboratory developed SARS-CoV-2 serology standards and protocols to ensure integrity and reproducibility across SeroNet’s studies.  

Standard Operating Procedures

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Laboratory Equipment

General SOPs

HPV Assays

SARS-CoV-2 Assays