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  HPV vaccine
  One shot of HPV vaccine protects long-term against cervical cancer
  Study shows women should be safe from cancer-causing HPV for at least 20 years and probably more after just one dose of vaccine instead of the usual two or three.
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  Different high-risk HPV infections don’t spur cancers at the same rate
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KRAS G12C
RAS drug discovery at Frederick National Laboratory reaches lung cancer patients in a clinical trial
A first-in-human study seeks to determine the drug’s safety and tolerability and to detect potential antitumor activity.
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  Did you know?
  
  About 30% of all human cancers are driven by mutations of the RAS family of genes. The RAS Initiative endeavors to better understand the RAS oncogene and discover its vulnerabilities to treat RAS-related cancers.
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  Importance of innovation Within FNL, innovation plays a pivotal role in delivering new and enhanced technologies that empower us to tackle essential scientific inquiries, enhance our services, and ultimately contribute to the wellbeing of patients.
  Vladimir Popov, Ph.D., MBA
- Scientific Series
BBO-10203
Drug blocking cancer-driving RAS-PI3K pathway enters clinical trials
Second drug candidate targeting RAS-related cancers developed by the RAS Initiative in partnership with BridgeBio Oncology Therapeutics and Lawrence Livermore National Laboratory to enter clinical trials.
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SeroNet study samples available to request
Investigators can request serological samples from SARS-CoV-2 studies through the SeroNet Study Collections.
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What do you enjoy about working at the Frederick National Laboratory? I enjoy coming to work every day because of the wonderful team we have.
Chris Karlovich, Ph.D.
About FNL
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In the 10-year period 2012-2022, the Vaccine Clinical Materials Program completed 300+ shipments supporting approximately 100 clinical trials across 45 products.

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Service & Maintenance Agreement for Environmental Test Chambers
Service & Maintenance Agreement for Microbial Detection System
Service Maintenance Agreement for De-Rouging, Passivation, Cleaning of WFI & Clean Steam Systems
Stable Clone Production for Anti-CD6 Monoclonal Antibodies
Stable Clone Production for Anti-CD6 Monoclonal Antibodies

One shot of HPV vaccine protects long-term against cervical cancer

Different high-risk HPV infections don’t spur cancers at the same rate

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Next deadline to apply: Sept. 2, 2025

Driving results through crisis and uncertainty: From Operation Warp Speed to the World

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National laboratories’ publication wins best paper award

FNL Patents

Application: NCEF Cryo-EM Training Program

Application: NCEF Cryo-EM Training Program