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  Join us for the 2026 RAS Initiative Symposium.
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  Importance of innovation Within FNL, innovation plays a pivotal role in delivering new and enhanced technologies that empower us to tackle essential scientific inquiries, enhance our services, and ultimately contribute to the wellbeing of patients.
  Vladimir Popov, Ph.D., MBA
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Preclinical data on potential treatment for RAS-driven cancers to be presented at AACR26
Studies on BBO-10203 and BBO-11818 will be presented in San Diego.
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About FNL
Did you know?

About 30% of all human cancers are driven by mutations of the RAS family of genes. The RAS Initiative endeavors to better understand the RAS oncogene and discover its vulnerabilities to treat RAS-related cancers.

Publications

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Below you'll find a list of all our scientific publications.

Only authors from the Frederick National Laboratory for Cancer Research are displayed.

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Directorate / Lab / Affiliation

AIDS Monitoring Laboratory

AIDS and Cancer Virus Program

Advanced Biomedical Computational Science

Advanced Cryo-Electron Microscopy Technology Group

Animal Diagnostics Laboratory

Animal Research Technical Support

Antibody Characterization Laboratory

Applied and Developmental Research Directorate

Basic Science Program

Bioinformatics and Computational Science

Biological Products Core

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National Cryo-Electron Microscopy Facility

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Protein Expression Laboratory

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Radiochemistry Support Group

Retroviral Evolution Section

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Small Animal Imaging Program

Tissue Analysis and Retroviral Protein Chemistry Core

Vaccine Clinical Materials Program

Vaccine, Immunity, and Cancer Directorate

Viral Evolution Core

Viral Oncology Section

Viral Persistence Section

Virus Isolation and Serology Laboratory

Apr1

2026

Ubiquitin-dependent recruitment of SLFN11 to chromatin is regulated by deubiquitinase (DUB) and RNF168

Res Sq

PMID 41994138

Wu Y, and 10 more

Bioinformatics and Computational Science › Advanced Biomedical Computational Science

Apr1

2026

Unraveling CD8 lineage decisions reveals that functionally distinct CD8+ T cells are selected by different MHC-I thymic peptides

Nat Immunol

PMID 41555085

Chen X, and 8 more

Bioinformatics and Computational Science › Advanced Biomedical Computational Science

Apr1

2026

ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation

EMBO J

PMID 41820617

Guiblet W, and 6 more

Bioinformatics and Computational Science › Advanced Biomedical Computational Science

Mar30

2026

UGT1A1 fragment analysis: genotyping the (TA)n variable repeat polymorphism for clinical applications

J Clin Lab Anal

PMID 41906410

Baugher R, Pike K, Plona T, Mellott S, Young T, Lawhorn H, Bocik W, and 1 more

Cancer Research Technology Program

Mar1

2026

Acid Ceramidase Inhibition Disrupts Ceramide Homeostasis and Induces Mitochondrial Apoptosis in IDH1-Mutant Oligodendroglioma

Res Sq

PMID 41928812

Zhang M, and 19 more

Laboratory Animal Sciences Program › Laboratory Animal Medicine

Mar1

2026

Annual trends and risk factors of late presentation of HIV at 19 referral hospitals in Indonesia: findings from the INA-PROACTIVE cohort

Lancet Reg Health Southeast Asia

PMID 41808690

INA-PROACTIVE Study Group (Grue L, Perodin J, Watkins K), and 36 more

Clinical Monitoring Research Program

Mar1

2026

BRAF V600E Expression in c-Kit+ Interstitial Cells of Cajal Drives Gastrointestinal Stromal Tumor Formation in Mice

Cancer Res Commun

PMID 41697759

Barrick C, Edmondson EF, and 8 more

Laboratory Animal Sciences Program › Molecular Histopathology Laboratory

Mar1

2026

COVID-19 vaccine immunogenicity in Mongolian adults with and without chronic hepatitis

BMC Infect Dis

PMID 41872755

Callier V, InVITE Study Team (Bonnett T, Burkey A, Cline-Cole E, Eyler A, Grue L, Kallon K, Lim C, Newell K, Njoh W, Sandrus J, Weyers S, Worthington C), and 7 more

Clinical Monitoring Research Program

Mar1

2026

Cyclin-E/A/CDK1/2 kinetic landscapes drive cell cycle phase-specific progression and guide Cyclin-E degradation strategy

J Chem Inf Model

PMID 41801818

Jang H, Nussinov R, and 4 more

Basic Science Program

Mar1

2026

Deep generative molecular design and its value in modern drug discovery

Expert Opin Drug Discov

PMID 41778634

Jang H, Nussinov R, and 3 more

Basic Science Program

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Frederick National Laboratory for Cancer Research is operated by Leidos Biomedical Research, Inc. for the National Cancer Institute.

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