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  Importance of innovation Within FNL, innovation plays a pivotal role in delivering new and enhanced technologies that empower us to tackle essential scientific inquiries, enhance our services, and ultimately contribute to the wellbeing of patients.
  Vladimir Popov, Ph.D., MBA
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Preclinical data on potential treatment for RAS-driven cancers to be presented at AACR26
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About FNL
Did you know?

About 30% of all human cancers are driven by mutations of the RAS family of genes. The RAS Initiative endeavors to better understand the RAS oncogene and discover its vulnerabilities to treat RAS-related cancers.

Publications

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Below you'll find a list of all our scientific publications.

Only authors from the Frederick National Laboratory for Cancer Research are displayed.

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Directorate / Lab / Affiliation

AIDS Monitoring Laboratory

AIDS and Cancer Virus Program

Advanced Biomedical Computational Science

Advanced Cryo-Electron Microscopy Technology Group

Animal Diagnostics Laboratory

Animal Research Technical Support

Antibody Characterization Laboratory

Applied and Developmental Research Directorate

Basic Science Program

Bioinformatics and Computational Science

Biological Products Core

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Mouse Modeling and Cryopreservation

Nanotechnology Characterization Laboratory

National Cryo-Electron Microscopy Facility

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Pharmacokinetics and Drug Analysis Group

Protein Expression Laboratory

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Radiochemistry Program

Radiochemistry Support Group

Retroviral Evolution Section

Retroviral Pathogenesis Section

Retrovirus-Cell Interaction Section

Small Animal Imaging Program

Tissue Analysis and Retroviral Protein Chemistry Core

Vaccine Clinical Materials Program

Vaccine, Immunity, and Cancer Directorate

Viral Evolution Core

Viral Oncology Section

Viral Persistence Section

Virus Isolation and Serology Laboratory

Jun1

2026

Spatial cellular order underlies locally-confined mechanisms of immune resistance in oropharyngeal cancer

Nat Commun

PMID 42288489

Kelly M, and 17 more

Cancer Research Technology Program

Jun1

2026

Sustained Prevention of SIVmac251 Acquisition in Vaccinated Macaques via delivery of SAMT-247 by Intravaginal Rings

Cell Rep Med

PMID 42302793

Alilin AN, Killoran KE, Kramer J, Breed MW, and 18 more

Laboratory Animal Sciences Program › Laboratory Animal Medicine

Jun1

2026

TriosCompass: a snakemake workflow for integrated detection of SNVs, indels, STRs, and structural de novo variants in parent-child trios

Bioinformatics

PMID 42162957

Zhu W, Yeager M, Jain K, Hicks B, and 4 more

Clinical Research Directorate › Cancer Genomics Research Laboratory

May1

2026

18F-FDG PET/CT is a quantitative tool to probe vascular inflammation and immune systemic metabolic activation in atherosclerotic nonhuman primates

EJNMMI Res

PMID 42213277

Crozier I, and 12 more

Clinical Monitoring Research Program

May1

2026

A first-in-class precision antibody conjugate targeting EGFR, mTOR, and PI3K to treat head and neck cancers

Res Sq

PMID 42183362

Thang L, Difilippantonio S, and 14 more

Laboratory Animal Sciences Program › Animal Research Technical Support

May1

2026

A high-penetrance intergenic variant at 9p21 confers melanoma susceptibility

Res Sq

PMID 42183343

Wang X, Liu J, Zhou W, Luo W, Vogt A, Jones K, Hicks B, and 49 more

Clinical Research Directorate › Cancer Genomics Research Laboratory

May1

2026

Antiretroviral therapy arrests natural selection on protective and disease-susceptible HLA-B alleles in HIB-1 infection

Proc Natl Acad Sci U S A

PMID 42044322

Carrington M, and 20 more

Basic Science Program › HLA Immunogenetics Section

May1

2026

Association of age with outcomes in adrenocortical carcinoma: a combined cancer registry and multi-omic analysis

Cancers (Basel)

PMID 42122281

Meyer TJ, and 4 more

Bioinformatics and Computational Science › Advanced Biomedical Computational Science

May1

2026

Co-occurring clonal hematopoiesis exhibits strong selection and high leukemia risk

Nat Commun

PMID 42168198

Zhou W, Jones K, Hutchinson A, Hicks B, and 57 more

Clinical Research Directorate › Cancer Genomics Research Laboratory

May1

2026

Co-Targeting Nuclear Export and Translation Initiation Uncovers a Therapeutic Vulnerability in Lethal Prostate Cancer

biorXiv

PMID 42146671

Edmondson E, and 21 more

Laboratory Animal Sciences Program › Molecular Histopathology Laboratory

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Frederick National Laboratory for Cancer Research is operated by Leidos Biomedical Research, Inc. for the National Cancer Institute.

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