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Scientists explore how the immune system ‘trains’ itself during a COVID-19 infection
Posted 12/1/2020It’s war. Invaders are afoot. Vigilant sentries spot them, signal for reinforcements, unite with other nearby sentries, and charge into battle. Soon, the “big guns” arrive, a squadron of well-armed, well-trained soldiers who strike deep into the invaders’ ranks.
This drama unfolds on a cellular and subcellular battlefield. It’s the immune system’s response to a SARS-CoV-2…
Dr. Jeffrey Lifson elected AAAS fellow
Posted 11/29/2020Jeff Lifson, M.D., has been elected a fellow of the American Association for the Advancement of Science (AAAS), joining 488 of his AAAS colleagues to be honored this year for their extraordinary achievements in advancing science.
The new fellows were formally announced in the AAAS News & Notes section of the journal Science on Nov. 27. An induction ceremony for the…
Serological Sciences Network to bolster understanding of COVID-19 immune response
Serological Sciences NetworkPosted 11/16/2020The National Cancer Institute (NCI) is leveraging the serological sciences expertise of the Frederick National Laboratory for Cancer Research (FNL) to address the COVID-19 pandemic through a new effort launched last month.
The Serological Sciences Network, or SeroNet, is a collaboration across 25 biomedical research institutions to enhance understanding of the immune…
Sixth annual interdisciplinary workshop focuses on high performance computing, cancer research, and COVID-19
Cancer Data Science Initiatives, Seventh Computational Approaches for Cancer Workshop (CAFCW21)Posted 11/10/2020The Computational Approaches for Cancer Workshop at SC20 fosters collaborations and future innovations to better understand, diagnose, treat, and prevent cancer.
On Nov. 13, clinicians, cancer biologists, mathematicians, computational scientists, biomedical engineers and data scientists worldwide will participate in the Sixth Computational Approaches for Cancer Workshop (…
Ruth Nussinov elected fellow of American Physical Society
Posted 11/5/2020Ruth Nussinov, Ph.D. says her election as a 2020 American Physical Society fellow is an especially gratifying recognition and for a very basic reason: “I am not a physicist.”
But her contribution to the field of biophysics and “extraordinary advancements in scientific understanding” led the APS’s Division of Biological Physics to nominate Nussinov as a society fellow.…
Frederick National Laboratory invention fills a gap with precise radiation measuring tool
Posted 11/3/2020When physicist Stephen Adler, Ph.D., joined the Frederick National Laboratory for Cancer Research (FNL), he quickly observed a gap in the tools to measure radiation doses in preclinical research.
Precise radiation doses are critical for many preclinical experiments with small animal models—doses which are typically in the few microcuries (µCi) range. However, when Adler…
Digital twin ideas lab: Innovative, cross-disciplinary research and a roadmap
Posted 10/21/2020A cancer patient’s “digital twin” would be the ideal resource for personalized treatment, and creating the technology stands as a grand challenge for the convergence of advanced computing technologies and oncology.
A digital twin is a computer replica of the systems and processes needed to run simulations without disrupting or harming the real-world object.
On July 6…
Technology Showcase leads to a model partnership
Partnership Development OfficePosted 10/20/2020The 2020 Technology Showcase was Maurice Hampton’s second time at the annual event, but his first opportunity to announce a collaboration that wouldn’t have been possible without it.
Hampton is the executive chairman and chief executive officer of early-stage biopharmaceutical company Telesis Therapeutics. In 2019, he drove three hours from Philadelphia to Frederick…
Novel prodrug platform enables drug delivery to lymphatic system
Posted 9/30/2020A team of researchers at the Frederick National Laboratory for Cancer Research (FNL) has developed a nanotechnology platform which targets the lymphatic system, an approach that could provide more effective treatment and therapies against infectious diseases and cancer.
The platform is based on poly(L-lysine succinylated) (PLS) polymer, a biodegradable polymer of the amino…
2020 Technology Showcase brings NCI and FNL technologies to a new audience
Posted 9/28/2020The 2020 Technology Showcase on September 9 brought well over 300 viewers for a half-day of presentations and panels on technology commercialization and collaboration. The annual event once again highlighted the capabilities of the Frederick National Laboratory for Cancer Research (FNL), National Cancer Institute (NCI), and greater Frederick region—but this year, with its…