Posted 3/15/2023
Severe forms of neurofibromatosis linked to disruptions in a protein partnership New research by Frederick National...
Posted 2/15/2023
To celebrate International Women and Girls in Science Day, we co-hosted a panel discussion on Feb. 10 with Woman to...
Posted 11/15/2022
The Biopharmaceutical Development Program (BDP) at Frederick National Laboratory is engineering cells into cancer...
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Victor Ssempijja: A data analyst who’s helping to diminish an epidemic
Clinical Monitoring Research ProgramPosted 4/15/2021
Victor Ssempijja remembers there being many fatherless households in his hometown in Uganda during his childhood. In fact, he says he could count the number of complete families on just his fingers. The other fathers had died of HIV and associated complications.
“I actually grew up thinking that men were not supposed to live long,” he said.
The situation is better…
Data set lets AI teach itself to analyze microscopy better
Posted 4/13/2021A data set doesn’t sound like a flashy scientific advance, but that impression belies a concept with the potential to enable eye-catching science.
Such is the case with CEM500K, a new data set created by Kedar Narayan, Ph.D., and Ryan Conrad in the Center for Molecular Microscopy at Frederick National Laboratory. As reported in eLife last week, it’s a cutting-edge resource…
An ember in the soul: A tribute to clinical trial participants
Posted 4/7/2021The National Cancer Institute is currently supporting more than 6,700 clinical trials.
That staggering statistic is dwarfed by the number of participants in those trials, many of whom are cancer patients. Even more astounding is that these numbers are for just this moment in time. The thousands of trials currently recruiting or underway are themselves a mere fraction of…
Digital twins for cancer care: Exploring a cross-disciplinary innovative approach
Cancer Data Science InitiativesPosted 4/5/2021Used successfully in several industries, digital twins have the potential to forge a path toward advances in cancer care and research. By melding computational science with the field of medicine, scientists aim to use digital twins to ultimately predict the effect of new therapies on cancer patients by using computer models without harming actual humans.
Frederick…
Metabolic mystery gives way, revealing driver of rare kidney cancer
Posted 3/23/2021Two scientists and their colleagues have uncovered a key activity driving a rare and deadly type of kidney cancer called hereditary leiomyomatosis and renal cell carcinoma (HLRCC).
Their study explains how altered metabolism “rewires” these cancer cells, allowing them to be more aggressive and malignant.
The new information illuminates a previously unknown aspect…
Program pioneers a path for Frederick’s science
Posted 3/15/2021As the winter of 1973 turned to spring, the Frederick Cancer Research Center (FCRC), the forerunner to the Frederick National Laboratory and the National Cancer Institute (NCI) at Frederick that exist today, neared the one-year mark since its opening. The more than 250 employees had made sound progress, given the challenges of converting the old Fort Detrick biowarfare…
A new institution for cancer research is born
Posted 3/15/2021On October 18, 1971, President Richard Nixon emerged from the U.S. Army Post Headquarters at Fort Detrick into the sunlight of one of Frederick’s signature autumn mornings. Nearby, a crowd of dignitaries, Army officers, and journalists from local and national news outlets had gathered to hear his remarks about the former biowarfare research facility. He greeted them, paused to…
FNL collaborates with FDA to establish best practices for single-cell RNA sequencing
Bioinformatics and Computational SciencePosted 3/10/2021Researchers from the Sequencing Facility and Biomedical Informatics and Data Science Directorate at the Frederick National Laboratory (FNL) collaborated with the U.S. Food and Drug Administration (FDA) and other research centers across the U.S. to conduct a benchmark study establishing best practices for high-throughput single-cell RNA sequencing.
The study, published in…
The Cancer Imaging Archive posts COVID-19 imaging data to benefit community
Posted 2/24/2021Publicly available data sets related to COVID-19 are appearing in an unexpected place—the Cancer Imaging Archive (TCIA), a project of the Division of Cancer Treatment and Diagnosis of the National Cancer Institute.
Since the start of the pandemic, researchers around the world have been racing to learn as much as possible about the virus—how it spreads, how to diagnose and…
New directorate expands serology capabilities
Vaccine, Immunity, and Cancer DirectoratePosted 2/23/2021As the Frederick National Laboratory for Cancer Research (FNL) expands its serology efforts in response to the COVID-19 pandemic, the biomedical research institution formed a new section dedicated to those efforts and the evaluation and standardization of immune responses to vaccines, infections and cancer.
Establishment of the Vaccine, Immunity, and Cancer Directorate…
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