Posted 3/15/2023
Severe forms of neurofibromatosis linked to disruptions in a protein partnership New research by Frederick National...
Posted 2/15/2023
To celebrate International Women and Girls in Science Day, we co-hosted a panel discussion on Feb. 10 with Woman to...
Posted 11/15/2022
The Biopharmaceutical Development Program (BDP) at Frederick National Laboratory is engineering cells into cancer...
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Public-private network ensures accuracy of COVID-19 antibody tests available in US market
Vaccine, Immunity, and Cancer DirectoratePosted 1/20/2022 Frederick National Laboratory for Cancer Research (FNL) plays a central role in a public-private network that has kept scores of substandard COVID-19 blood antibody tests out of circulation and helped ensure that marketed tests give accurate results.
This critical pandemic response is detailed in a scientific study published January 12 in the journal Microbiology…
Growing cancer cells in 3D -- not just 2D -- might improve preclinical drug development
Antibody Characterization LaboratoryPosted 1/18/2022One way to improve the success rate for new cancer drugs might be to test them in a three dimensional (3D) environment that mimics real life better than the two-dimensional (2D) set-up of a flat culture dish, according to a new study that examined thousands of lung cancer proteins grown under both conditions.
About 95 percent of experimental drugs for lung cancer fail…
Scientists develop new concept for hard-to-treat cancers like mesothelioma
Laboratory Animal Sciences ProgramPosted 1/13/2022Think of a tumor and you might envision a disorganized mass. But tumors can also form a thin sheet over a surface. These can be hard to treat, especially when the surface has wrinkles and crevices. But there may be a new approach.
Solid tumors can be successfully removed with surgery and residual cells destroyed. But cancers like the asbestos-related lung malignancy…
Partnership with FCC aims to support the next generation of STEM in Frederick
Partnership Development OfficePosted 1/11/2022
The Frederick National Laboratory for Cancer Research (FNL) signed a new memorandum of understanding (MOU) with Frederick Community College (FCC) to establish a closer partnership to support the future science, technology, engineering and mathematics (STEM) workforce in Frederick.
“As a scientific organization, we are eager to connect with and inspire the next…
Passion for research and a drive to improve public health motivate Ligia Pinto to embrace challenges of COVID response
Vaccine, Immunity, and Cancer DirectoratePosted 1/6/2022The coronavirus pandemic was heating up and so was the urgent need for blood tests to confirm infections. It was spring 2020, and a host of companies were developing and submitting newly minted tests to the Food and Drug Administration (FDA) for potential Emergency Use Authorization (EUA) approval.
The FDA had to know if the tests were accurate. So the agency contacted…
New partnership with Morehouse School of Medicine on health equity
Partnership Development OfficePosted 12/21/2021The Frederick National Laboratory for Cancer Research (FNL) and Morehouse School of Medicine (MSM) have announced a new strategic partnership to support the mutual exchange of training and research expertise, with a focus on research to improve cancer patient care through precision medicine.
“Morehouse School of Medicine’s mission is to train the next generation of…
Nanotechnology Characterization Laboratory leverages growing industry interest in the technology
Nanotechnology Characterization LaboratoryPosted 12/16/2021The Nanotechnology Characterization Laboratory is working with industry partners to bolster the use of nanotechnology in drug development and delivery as the interest in the promising technology expands.
“Pharma has initially been hesitant to get into nano because it’s too much risk versus reward,” said Jeffrey D. Clogston, Ph.D., the Physicochemical Characterization…
Study shows an increase in immune response induced by the HPV vaccine in middle-aged men
Vaccine, Immunity, and Cancer Directorate, HPV Serology LaboratoryPosted 12/14/2021A study conducted in part by researchers of the Frederick National Laboratory for Cancer Research (FNL) HPV Serology Laboratory showed middle-aged men who received three doses of the quadrivalent human papillomavirus (HPV) vaccine experienced a robust immune response to vaccine antigens—critical for long-term protection against HPV.
The human papillomavirus (HPV) is one…
Rapid response team grows NIH study network during pandemic while keeping participants safe
Clinical Monitoring Research ProgramPosted 10/28/2021In the push to find treatments for the novel coronavirus, a Frederick National Laboratory team helped enroll thousands of participants in clinical trials and brought on board community hospitals as new study sites to join the research effort amid the pandemic.
The partnership with community-based hospitals as clinical trial sites was highlighted in a recent commentary in…
Biomarker analysis reveals clues to COVID-19 disease severity
Neutrophil Monitoring Laboratory, Immunological Monitoring LaboratoryPosted 10/21/2021Predicting disease severity from a SARS-CoV-2 infection has been an elusive but critical need in addressing the COVID-19 pandemic, as some patients experience mild symptoms while others develop fatal complications. As scientists try to determine what contributes to infection levels and mortality, several medical signs are providing potential answers.
The Neutrophil…
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