Clostridium botulinum stained with Gentian violet. The bacterium produces a nerve toxin, which causes botulism, a rare, but serious paralytic disease. Image courtesy of the Centers for Disease Control and Prevention.

The Nanotechnology Characterization Laboratory (NCL) is collaborating with the Army to develop a candidate vaccine against botulism.

Under a collaboration agreement between the National Cancer Institute and the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), NCL scientists will produce nanoparticle formulations for four compounds that block the activity of botulism-causing nerve toxins, which are among the most lethal of all poisons.

Frank McCormick

The Frederick National Laboratory for Cancer Research will spearhead a national R&D initiative focused on mutations in a family of genes called Ras, which play a role in 33 percent of all human cancers, including 90 percent of pancreatic cancers.

Frank McCormick

Frank McCormick, Ph.D., director of the Helen Diller Family Comprehensive Cancer Center at the University of California, San Francisco, and associate dean of the UCSF School of Medicine, has signed a consulting agreement with SAIC-Frederick Inc. to work with the Frederick National Laboratory for Cancer Research (FNLCR), on behalf of the National Cancer Institute (NCI), to develop a proposal for intensive study of cancer cells driven by mutations of the RAS gene.

IRP XMRV Working Group, from left: Vineet KewalRamani, Ph.D., head, Model Development Section, DRP (NCI); Rachel Bagni, Ph.D., Molecular Detection and Viral Technology, PEL (SAIC-Frederick); Jeffrey Lifson, M.D., director, ACVP (SAIC-Frederick); Alan Rein, Ph.D., head, Retrovirus Assembly Section, DRP (NCI); James Hartley, Ph.D., head, Technology Development, PEL (SAIC-Frederick); Mary Kearney, Ph.D., head, Translational Research, DRP (NCI); and Stuart Le Grice, Ph.D., head, RT Biochemistry Section, DRP

In July 2012, members of a multidisciplinary research team of both SAIC-Frederick and NCI Center for Cancer Research scientists were recognized with the NIH Director’s Award for their outstanding work to rapidly evaluate a potential threat to the nation’s blood supply.