Scientists and clinicians whose discoveries have shaped the understanding of HIV disease will provide updates on the...
There are many paths for women to travel to find success in science. That was a crucial theme conveyed by the four...
Frederick National Laboratory researchers identified a vitamin A derivative (retinoid) that when combined with a...

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Canine data commons lets dogs with cancer help humans

Bioinformatics and Computational SciencePosted 4/26/2023
Dogs and humans have been companions throughout recorded history. Our four-legged friends appear in early written tales, such as the Mesopotamian poem The Epic of Gilgamesh, and are mentioned by name in ancient Egyptian inscriptions. In prehistoric gravesites worldwide, dogs are found laid to rest alongside humans. They’ve been with us through thick and thin, and we have…

AI predicts the aggressiveness of a childhood cancer

Bioinformatics and Computational SciencePosted 4/18/2023
By training computer models to assess pathology images of rhabdomyosarcoma tumors, researchers hope to help doctors better tailor treatments to patients. Researchers at the Frederick National Laboratory for Cancer Research and the National Cancer Institute developed an artificial intelligence-based system that can anticipate the severity of cases of a childhood cancer…

FNL scientists to present multiple studies at American Association for Cancer Research Annual Meeting

Partnership Development OfficePosted 4/13/2023
Investigators from the Frederick National Laboratory for Cancer Research will share their latest work in clinical trials, bioinformatics cancer models, imaging technology initiatives, and more at the American Association for Cancer Research Annual Meeting 2023. More than 30 abstracts by FNL investigators will be presented in mini symposia and poster sessions…

Experimental flu vaccine shows protection against many strains

Cancer Research Technology ProgramPosted 4/4/2023
A research group including Frederick National Laboratory scientists has taken an early step toward a universal influenza vaccine that appears to protect against many strains, including the closely watched H5N1 bird flu. Human trials are under way. Conventional seasonal flu vaccines target the rapidly mutating head of the hemagglutinin (HA) protein on the virus particle, so…

Biotech Connector: Next-Generation Vaccine Formulation and Delivery

Nanotechnology Characterization Laboratory, Cancer Research Technology ProgramPosted 3/28/2023
Maryland scientists came together earlier this month to discuss next-generation vaccine formulation and delivery, as the Biotech Connector speaker series returned to Frederick. The Biotech Connector is a quarterly networking and speaker series, hosted by the Frederick National Laboratory for Cancer Research and Frederick County Chamber of Commerce. The scientific event…

Untangling the complex genetics of neurofibromatosis

Protein Expression Laboratory, Advanced Cryo-Electron Microscopy Technology Group, Cancer Research Technology ProgramPosted 3/15/2023
Severe forms of neurofibromatosis linked to disruptions in a protein partnership New research by Frederick National Laboratory (FNL) researchers and their colleagues takes an important step toward explaining complex mutations in a gene called NF1 that is known to cause a disorder known as neurofibromatosis type 1. The study also has potential implications in research…

Trends observed in nearly 20 years of nanotech data offer insight

Nanotechnology Characterization Laboratory, Cancer Research Technology ProgramPosted 3/7/2023
Scientists at Frederick National Laboratory for Cancer Research and the National Cancer Institute have analyzed nearly two decades’ worth of data about biomedical nanotechnology studies, revealing patterns never seen before. While that may seem exclusively like the domain of laboratory coats and computers, removed from the realm of public concern, its appearance belies…

Women pursuing science add value to the endeavor, with support from mentors and allies

Posted 2/15/2023
To celebrate International Women and Girls in Science Day, we co-hosted a panel discussion on Feb. 10 with Woman to Woman Mentoring and Hood College where successful women in science discussed their chosen career paths, allyship and mentorship in science and strategies for advancement. This was the second annual Women in Science event and the first in-person. Women…

Looking Back, Looking Ahead: 2022’s AI Symposium Charted Paths for Cancer Research Progress

Bioinformatics and Computational Science, Cancer Research Technology Program, Cancer Data Science InitiativesPosted 2/2/2023
Last year, some of the world’s top leaders in the field came together to discuss the progress of artificial intelligence (AI) applications in cancer research and clinical care at a scientific symposium hosted by Hood College and Frederick National Laboratory (FNL). It was one of several large scientific gatherings in Frederick in 2022 with implications for the new year…

Encephalitis vaccine does well in early clinical trial; commercial development pending

Vaccine Clinical Materials ProgramPosted 12/21/2022
Commercial development of a vaccine against three types of mosquito-borne equine encephalitis viruses — which are classified as potential biological warfare agents and can be fatal in humans — has begun following a government-led phase I clinical trial conducted with materials produced by the Frederick National Laboratory’s Vaccine Clinical Materials Program. No therapies…