The first conference held under the auspices of Frederick National Laboratory’s (FNL’s) Scientific Standards Hub , an...
Technologies invented and patented by researchers at the Frederick National Laboratory for Cancer Research are on...
Research led by the Frederick National Laboratory for Cancer Research (FNL) and Gilead Sciences shows the potential for...

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Scientific Standards Hub’s inaugural conference tackles standards in protein production

Protein Expression LaboratoryPosted 4/5/2024
The first conference held under the auspices of Frederick National Laboratory’s (FNL’s) Scientific Standards Hub, an initiative formed to address the scientific reproducibility crisis, has just wrapped up. The two-day event, dubbed The α-Twists and β-Turns of Recombinant Protein Production, examined standardization in laboratory and commercial production of proteins. A…

Investigators in multiple teams set to share latest research at AACR Annual Meeting

Molecular Characterization Laboratory, RAS Initiative, Cancer Data Science InitiativesPosted 4/3/2024
Talks and posters to be presented at the 2024 American Association for Cancer Research annual meeting reflect the breadth and depth of science conducted at the Frederick National Laboratory for Cancer Research (FNL), with topics including liquid biopsy, Lynch syndrome, a new potential treatment for KRAS-related cancers, and ways to achieve cell death in lung cancer.…

Global experts to illuminate state of HIV/AIDS research and patient care at scientific symposium

HIV in 2024: Progress, Problems & ProspectsPosted 3/25/2024
Scientists and clinicians whose discoveries have shaped the understanding of HIV disease will provide updates on the status of HIV/AIDS research and patient care and discuss approaches to overcome major remaining challenges at a scientific symposium hosted by Hood College in partnership with the Frederick National Laboratory for Cancer Research (FNL) on September 23-25…

Biotech Connector showcases how better antibodies enable better science

Partnership Development OfficePosted 3/5/2024
Antibodies are naturally produced by the human body’s plasma cells and trigger an adaptive immune response against invading pathogens. Laboratory-produced antibodies are engineered to restore, enhance, modify or mimic the immune system's attack on cells that aren't wanted, thereby proving invaluable in cancer research. Speakers at a recent Biotech Connector…

Study establishes measurement for factor affecting immune response to HIV

Basic Science ProgramPosted 2/28/2024
HIV ravages the immune system in people who acquire it, but not everyone is affected equally. In some of these individuals, the effects of the virus don’t manifest as swiftly as in others. Scientists have long recognized that people’s genes and the proteins they encode play a role in why this is. Now, a team in Frederick National Laboratory’s Basic Science Program and…

Biopharmaceutical Development Program embarks on new work for targeted cancer therapy

Biopharmaceutical Development ProgramPosted 2/27/2024
The Biopharmaceutical Development Program (BDP) has entered a new area of investigational cancer treatment development: an Antibody-Drug Conjugate (ADC). The research is a collaboration of the Frederick National Laboratory for Cancer Research (FNL) and the Dana-Farber Cancer Institute with funding provided by the National Cancer Institute’s Division of Cancer Treatment and…

‘What a scientist looks like’: Women in science describe adversity and success 

Posted 2/22/2024
There are many paths for women to travel to find success in science. That was a crucial theme conveyed by the four panelists at Women in Science Speak 2024. The panel marked the International Day of Women and Girls in Science and celebrated empowerment and mentorship among women in science. Woman to Woman Mentoring, Inc.; Frederick National Laboratory; and Hood College co-…

Conference to celebrate and support Black cancer researchers 

Posted 2/21/2024
The cancer community will come together for a two-day conference designed to celebrate Black contributions in cancer research and to connect future investigators and collaborators, in order to pave the way for the next generation of Black cancer research professionals.  Black in Cancer, a US/UK-based organization and the Frederick National Laboratory for Cancer Research…

Mickey Williams’ lifelong love for science enters emeritus era

Molecular Characterization LaboratoryPosted 2/15/2024
Mickey Williams, Ph.D., jokes that he was “somewhat doomed to become a molecular biologist” from the very start, born within mere hours of a milestone in the field. The same day in 1953 that Francis Crick and James Watson heralded their discovery of DNA’s double-helix structure — “the secret of life,” Crick triumphantly called it at The Eagle pub in Cambridge—Williams…

Specific retinoid shrinks immune checkpoint-resistant lung cancers in mice

Posted 2/7/2024
Frederick National Laboratory researchers identified a vitamin A derivative (retinoid) that when combined with a standard immunotherapy will shrink otherwise checkpoint-resistant lung tumors in mice, a potential step toward human clinical trials to improve lung cancer treatment. The research, described in Scientific Reports, focused on all-trans-retinoic acid (ATRA), a…