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Clinical Safety Office supports patient safety monitoring for mpox clinical trial in Africa
Clinical Monitoring Research ProgramPosted 6/13/2023
A new clinical study in Africa is testing an antiviral treatment for patients with mpox (previously known as monkeypox). This is the latest project for the Frederick National Laboratory for Cancer Research’s Clinical Monitoring Research Program, which specializes in supporting clinical trials in domestic and international settings.
The Clinical Safety Office, under…
First study of people with HIV on long-term ART shows cognitive decline
Clinical Research DirectoratePosted 6/7/2023People with HIV on long-term antiretroviral therapy show signs of brain damage and cognitive impairment on a battery of imaging, laboratory, and functional tests, and they report a greater degree of difficulty with the routine tasks of everyday life, according to a new study.
The study, published in April in the journal Neurology, is the first to gauge cognitive changes in…
Blood-based tests may offer noninvasive way to determine immunotherapy candidates
Molecular Characterization Laboratory, Clinical Research DirectoratePosted 6/1/2023Blood-based tests that identify cancer markers may offer a noninvasive way to determine if a patient is a candidate for immunotherapy, according to a Frederick National Laboratory for Cancer Research study to be presented at the 2023 Annual Meeting of the American Society for Clinical Oncology, June 2-6 in Chicago.
Chris Karlovich, Ph.D. of the Frederick National…
Biotech Connector recap: Shedding light on human maladies
Posted 6/1/2023Three scientists from the region presented innovative imaging techniques and discussed how they are leveraging them to advance cancer research and ultimately improve human health at the Biotech Connector seminar on Wednesday, May 17, the second in this year’s series sponsored by the Frederick National Laboratory for Cancer Research and the Frederick County Chamber of Commerce…
A single dose of HPV vaccine may provide adequate protection
Vaccine, Immunity, and Cancer DirectoratePosted 5/31/2023A growing body of evidence suggests that a single dose of vaccine against cancer-causing human papilloma virus (HPV) may protect as well as the standard two-or-more dose regimen. This would make it easier to protect more women, especially in low-income areas where vaccine access is scarce.
A study published recently in The Lancet Global Health strengthens the case, with a…
Three projects awarded LDER funding to explore innovations
Partnership Development OfficePosted 5/22/2023Each year, the Frederick National Laboratory offers its scientists an opportunity to compete for funding to conduct the research they view as critical to advance biomedical research but is outside the scope of their daily research activities.
This year, three proposals earned funding through the program, known as the Laboratory Directed Exploratory Research (LDER) program…
FNL joins BIO International panel to tackle tough questions about AI in oncology, promote partnerships
Partnership Development OfficePosted 5/19/2023
Is your billion-dollar oncology artificial intelligence (AI) cutting-edge technology, or is it artificial ignorance? That’s the question Frederick National Laboratory’s Maggie Scully, Ph.D., and a panel of industry experts seek to tackle at the BIO International Convention in Boston on June 7.
Karim Budhwani, Ph.D., DLA, CEO-scientist of CerFlux, Inc., who will be…
Study Explores Type 1 Diabetes Vaccine
Bioinformatics and Computational Science, Advanced Biomedical Computational SciencePosted 5/18/2023A research collaboration has made early progress toward a potential vaccine for type 1 diabetes, a long-sought goal for an autoimmune disease that affects more than 1.5 million Americans.
The team, including Frederick National Laboratory computational scientist David Bell, previously discovered a new protein antibody in type 1 diabetes patients. The antibody, X-idiotype,…
Investigating the Immune Response to SARS-CoV-2
Vaccine, Immunity, and Cancer DirectoratePosted 5/11/2023A new test detects exposure to viruses that cause COVID-19 and their relatives. Research using it could aid efforts to protect against infections.
A team at the Frederick National Laboratory for Cancer Research developed a test capable of assessing exposure to the virus that causes COVID-19 and to a selection of its variants and viral relatives, all from a minute amount…
Vaccine tested for malaria and other mosquito-borne diseases
Clinical Monitoring Research ProgramPosted 5/5/2023A research group that includes scientists from the Frederick National Laboratory for Cancer Research has shown that an experimental vaccine designed to simultaneously protect against malaria, Zika, and a host of other mosquito-borne diseases safely provokes a strong immune response when tested in human volunteers. The next step will be to see if the vaccine blocks infection in…