Posted 4/5/2024
The first conference held under the auspices of Frederick National Laboratory’s (FNL’s) Scientific Standards Hub , an...
Posted 1/25/2024
Technologies invented and patented by researchers at the Frederick National Laboratory for Cancer Research are on...
Posted 1/9/2024
Research led by the Frederick National Laboratory for Cancer Research (FNL) and Gilead Sciences shows the potential for...
All News
August 31 Biotech Connector to Explore Advances in Protein Production
Center for Innovation and Strategic Partnerships, Partnership Development OfficePosted 8/21/2023
Proteins—large molecules composed of amino acids—perform an array of essential roles with the body, from catalyzing chemical reactions to providing structure to cells. As such, they are critical tools for a variety of biomedical research and gene therapy applications. However, generating the large yields of high-quality proteins needed for research and the clinic is no…
Performance varies widely in commercial and in-house COVID-19 blood antibody tests
Vaccine, Immunity, and Cancer DirectoratePosted 8/15/2023Many different blood tests are available for the COVID-19 virus to detect infection and to evaluate antibody responses developed after infection or vaccination. But not all tests hold to a standard ensuring that their results will be consistent with those of other similar tests. A new study addresses this issue.
A team of scientists from the Vaccine, Immunity and Cancer…
Case study links inflammation to HIV persistence in specific scenarios
AIDS and Cancer Virus ProgramPosted 8/7/2023A years-long case study has potentially identified another factor with which HIV treatment efforts must contend: Inflammation could be a linchpin in the virus’ overexpression in some people.
The findings come from the treatment of a person living with HIV. The study, led by the HIV Dynamics and Replication Program at the National Cancer Institute at Frederick and the…
End of NCI-MATCH trial positions precision medicine and genetic sequencing for next big push
Molecular Characterization LaboratoryPosted 8/3/2023NCI-MATCH, one of the largest cancer precision medicine clinical trials to date, closed in 2023 and its follow-on studies will use a similar model to test combinations of treatments, evaluating a patient’s immune system prior to pairing the patient with immunotherapy against their cancer.
The Molecular Analysis for Therapy Choice (NCI-MATCH) clinical trial was sponsored by…
Faster workflows boost drug discovery in natural product-based screening
Posted 7/26/2023Plants, marine invertebrates, and microbes have been a major source of novel drugs against cancer, viruses, and fungal diseases. New isolation methods are making it faster and easier to discover these natural products.
To encourage ongoing drug development from natural products, a collaboration of government and contractor scientists demonstrated accelerated methods of…
Two key drivers of hereditary kidney cancer are identified
Laboratory Animal Sciences ProgramPosted 7/13/2023An international research collaboration including scientists from the Frederick National Laboratory has identified two key drivers of a hereditary kidney cancer and opened new possibilities for therapeutic approaches to a disease whose current treatment is largely surgerical.
The scientists implicated two proteins that work cooperatively to drive tumor formation in Birt-…
Panel at BIO International Convention provides navigation tips and resources to avoid AI pitfalls
Partnership Development Office, Center for Innovation and Strategic PartnershipsPosted 7/10/2023Artificial intelligence has rapidly become a buzzword that evokes fear and hope. A recent panel discussion dug into this issue at the 2023 BIO International Convention, one of the world’s largest biotech partnering events, attracting more than 14,000 biotech leaders to Boston this year.
The discussion, “Is Your Billion-Dollar Oncology AI Cutting-Edge Technology or Is It…
National Science Foundation grant provides PhD student experience with machine learning under FNL mentor
Cancer Data Science Initiatives, Partnership Development OfficePosted 6/27/2023
When Chloe Thangavelu, a Ph.D. student at the University of California, Irvine, received funding from the National Science Foundation for a six-month internship, she eagerly set out to find an internship where she could combine her biological and computational expertise and gain experience with machine learning.
That’s why she reached out to the Frederick National…
Clinical Safety Office supports patient safety monitoring for mpox clinical trial in Africa
Clinical Monitoring Research ProgramPosted 6/13/2023
A new clinical study in Africa is testing an antiviral treatment for patients with mpox (previously known as monkeypox). This is the latest project for the Frederick National Laboratory for Cancer Research’s Clinical Monitoring Research Program, which specializes in supporting clinical trials in domestic and international settings.
The Clinical Safety Office, under…
First study of people with HIV on long-term ART shows cognitive decline
Posted 6/7/2023People with HIV on long-term antiretroviral therapy show signs of brain damage and cognitive impairment on a battery of imaging, laboratory, and functional tests, and they report a greater degree of difficulty with the routine tasks of everyday life, according to a new study.
The study, published in April in the journal Neurology, is the first to gauge cognitive changes in…
Media Inquiries
For all media related questions please contact:
Mary Ellen Hackett
Manager, Communications Office