Portrait of Leonard Freedman

FREDERICK, Md. -- Leonard P. Freedman, Ph.D., has been named chief science officer at the Frederick National Laboratory for Cancer Research, effective this November. He joins the FNL staff after six years as founding president of the Global Biological Standards Institute.

Signing ceremony at Mount St. Mary's University Frederick campus, October 9, 2018. Photo courtesy Mount St. Mary's University. 

FREDERICK, Md. -- The Frederick National Laboratory for Cancer Research is expanding its commitment to educate the next generation of scientists and foster academic research collaborations by signing a new partnership agreement with Mount St. Mary’s University.  

Beverly Keseling, (retired) manufacturing manager at BDP, studies PVSRIPO on an inverted microscope. 

FREDERICK, Md. -- The development of a modified poliovirus to treat glioblastoma, a deadly form of brain cancer, is one of the latest examples of the Frederick National Laboratory for Cancer Research stepping in to fill a critical need that few others could meet with developing and manufacturing novel biological agents for early-phase clinical trials. 

Eric Stahlberg portrait

FREDERICK, Md. -- Eric Stahlberg, Ph.D., has been named director of Biomedical Informatics and Data Science (BIDS) at the Frederick National Laboratory for Cancer Research in a move that will amplify his role in building partnerships in high-performance computing and data science in cancer research. There was an exceptional slate of candidates for this position, reflecting the importance of this position. Dr. Stahlberg begins his appointment on September 29.

An Orbital Sciences Corporation Antares rocket is seen as it launches from Pad-0A at NASA's Wallops Flight Facility, Thursday, January 9, 2014, Wallops Island, VA.

FREDERICK, Md. -- The Frederick National Laboratory for Cancer Research is taking its science to new heights – with an experiment rocketing into orbit around the Earth. 

The aim is to grow protein crystals in the weightlessness of space where, beyond the full influence of Earth’s gravity, they might proliferate more easily and become larger and more perfect than those cultivated on the Earth’s surface. The launch is scheduled for this fall.

A koilocyte is a squamous epithelial cell that has undergone structural changes as a result of infection by human papillomavirus (HPV). This image of a koilocyte shows human ectocervical cells (HEC) expressing HPV-16 E5 oncoprotein, and immortalized with HPV-16 E6 and E7 oncoproteins. Formation of koilocytes requires cooperation between HPV E5 and E6 oncoproteins. The cell culture is stained with hematoxylin and eosin (H&E).

FREDERICK, Md. -- A new chemical test available through the Frederick National Laboratory for Cancer Research could accelerate human papillomavirus (HPV) research by detecting 40 percent more HPVs than the current gold standard research test. 

There are upwards of 100 human papillomaviruses (HPVs), and these viruses can cause abnormal tissue growth and other changes to cells. Prolonged infection with certain types of HPV can cause cancer.   

Three-dimensional model of Simian Immunodeficiency Virus (SIV). National Cancer Institute image. Image by Sriram Subramaniam and Donald Bliss.

FREDERICK, Md. -- A new study led by investigators from the Frederick National Laboratory for Cancer Research in collaboration with colleagues from the Oregon Health and Science University (OHSU) utilizing a nonhuman primate model infected with Simian Immunodeficiency Virus (SIV) could have significant implications for future research into the prevention and potential cure of Human Immunodeficiency Virus (HIV). 

Ulrich Baxa and Natalia De Val Alda look at the Titan Krios microscope at the Frederick National Laboratory.

FREDERICK, Md. -- Nearly one-third of all human cancers are driven by mutations in RAS genes, including almost all pancreatic cancers. Treating these cancers has puzzled scientists for decades, and many RAS proteins are considered virtually undruggable. 

Human white blood cells with internalized particles (blue is cell nucleus, red is membrane, and green is RNA nanoparticles). Submitted by Marina Dobrovolskaia.

FREDERICK, Md. -- The Frederick National Laboratory for Cancer Research is opening potential new avenues for coaxing the human immune system to fight cancer and other diseases through microscopic particles, or nanoparticles.

The use of nanoparticles to transport drugs to cancer cells is a growing field that has piqued scientists’ interest over the last two decades. Nanoparticles show potential because they can directly target and treat cancer cells. 

Instituto Nacional de Cancerologìa (National Cancer Institute of Mexico)

FREDERICK, Md. -- The Frederick National Laboratory for Cancer Research will extend its scientific mentoring across international borders for the first time by offering postdoctoral research fellowships to scientists under an agreement with the National Cancer Institute of Mexico (INCan).

Under a three-year Memorandum of Understanding, the two institutions will cooperatively develop and launch a pilot program that will provide education and training in areas of mutual interest in cancer research.