Supporting the Human Tumor Atlas Pilot Project

The Human Tumor Atlas Pilot Project (HTAPP) was initiated to contribute to the Human Tumor Atlas Network (HTAN), an NCI-funded research network under the Cancer Moonshot^SM Initiative, with a goal to create dynamic 3D maps of tumors and precancerous lesions (i.e., tumor atlases), which aim to offer a comprehensive description of the dynamics of the molecular, cellular, and physiological events associated with individual tumor cells, the tumor mass itself, the tissue of origin, and sites of metastases.  

The Biospecimen Research Group managed the pilot project and closely worked with experts across the United States to lay the foundation for future human tumor atlas efforts.  

The pilot project contributed pilot-scale, single-cell molecular characterization data for seven tumor types using multiple sequencing and spatial imaging assays, sharing them alongside optimized protocols and computational pipelines.  

The data generated under HTAPP, along with protocols and computational tools used, are accessible via various HTAN channels such as the HTAN Portal. 

For any further information related to the Human Tumor Atlas Pilot Project, please feel free to contact: Yuriko Mori, M.D., Ph.D., at BRGSupport@nih.gov.