Pharmacokinetics of nanomedicines in rats
NCL-02
The Nanotechnology Characterization Lab (NCL) will evaluate the pharmacokinetics of a nanoparticulate formulation in rats using a novel stable isotope tracer ultrafiltration assay (SITUA), developed in-house. Blood samples will be collected at various timepoints to analyze encapsulated, free-unbound, and protein-bound drug concentrations, as well as noncompartmental pharmacokinetics to complement preclinical bioequivalence evaluations.
