Standardized serology assays, reagents, and procedures are critical to ensure data quality and allow comparison of results from different studies and vaccines.

The Vaccine, Immunity, and Cancer Directorate’s Serology Laboratory launched two initiatives to address the need for standardization and harmonization of serological assays for anti-HPV and SARS-CoV-2 antibody testing. Efforts for HPV are co-funded by the National Cancer Institute and Bill and Melinda Gates Foundation, while the efforts for SARS-CoV-2 are funded by the National Cancer Institute.

Results from these efforts will facilitate decision-making on new vaccine recommendations. 

HPV Operating Procedures developed by the Serology Laboratory are available to download.