Person of Contact Josh Wynne and Connor Cigrang (
Proposal Due Date Tuesday, November 28, 2023 (Closed 5 months 4 weeks ago)
  • Research Category Research & Development Services & Subcontracts
  • Solicitation Number S23-093
  • NCI OA Contract Number 75N91019D00024 – NCI-FFRDC


Today, many data science efforts seek to leverage established technologies and operationalize data infrastructure platforms to meet the Findable, Accessible, Interoperable and Reusable (FAIR) data principles. While established technologies can be engineered to accept data from more researchers, improve dashboards, and refine search capabilities, these technologies fail to improve the quality, standardization, and timeliness of data availability for data collected across thousands of labs and health care institutions. Experimental efforts often fail to collect the fidelity of data provenance, calibration information, experimental protocol information, and context needed to reliably test for experimental reproducibility. Furthermore, established technologies are limited in their ability to integrate data from multiple sources and support intuitive multi-source exploration or data analysis (including through Artificial Intelligence/Machine Learning (AI/ML)). Critical biomedical data usage by appropriate stakeholders can be impeded by access limitations, a lack of interoperability across hundreds of siloed data platforms, and a lack of robust, reusable methods to protect data privacy and security. At its crux, these limitations make it difficult to leverage data from thousands of labs, health care institutions, and research centers because each entity tends to manage data using incompatible biomedical dialects.

The RFP seeks to revolutionize data integration and usability approaches by making it easier to connect biomedical research data from thousands of sources and overcome barriers caused by incompatible data dialects. The BDF Toolbox project will advance data fabric capabilities to address the challenges around data integration, data usability, and incompatible biomedical dialects. Areas of technical emphasis include:

• Automated data collection to lower barriers to high-fidelity, timely access to computationally ready research data across labs and health record systems.
• AI-assisted curation to prepare, connect, and harmonize multi-source data for analysis at scale.
• Intuitive exploration to enable advanced, intuitive, human-centered data exploration and dashboards for use by diverse stakeholders and decision-makers across disciplines and health literacy levels.
• User testing to evaluate data fabric tools across diverse users – including researchers, clinicians, and patients - to create tools that will be enthusiastically adopted.

Objectives to be achieved include but are not limited to the following:

• Lowering the barriers to data collection,
• Providing reusable approaches to support multi-source data preparation for analysis at scale,
• Providing intuitive dashboards for data exploration usable by diverse users in the cancer community,
• Facilitating evaluation of data usability by diverse stakeholders in the cancer community.

Proposal Instructions

To be considered for award, offers must be received at the location specified above by CLOSE OF BUSINESS (COB) ON 14 NOVEMBER 2023. Offers must be clearly identified with the Solicitation/RFP Number listed above. Award(s) are intended to be either Cost Reimbursable or Time and Material type. For the full solicitation package, please reach out to Josh Wynne and/or Connor Cigrang ( /

Modified By Date Modified Sort ascending Comment
Connor Cigrang

Amendment 2 to the Solicitation S23-093 has been Executed by Leidos Biomedical Research. 


The purpose of this Amendment is to provide Answers to a comprehensive list of Questions received in response to this Solicitation prior to the Question due-date of October 27,2023 at 5 PM (Est.). To receive the Amendment, Offerors shall contact Mr.'s Connor Cigrang and Josh Wynne. 

Connor Cigrang

Amendment 1 to the Solicitation S23-093 has been Executed by Leidos Biomedical Research. 

The purpose of this Amendment is to modify Solicitation provisions “C. Solicitation Package” and “F. Proposal Instructions to Offerors”. To Receive the Amendment and applicable Attachments, Offerors shall contact Mr.'s Connor Cigrang and Josh Wynne. 

Connor Cigrang

Update the Solicitation Due-Date from November 14, 2023 to November 28, 2023.  


Connor Cigrang

To guarantee a response from Leidos Biomedical Research, all Questions are due to the attention of Connor Cigrang ( and Josh Wynne ( no later than Close of Business (5:00 PM, EST.) on Friday, October 27, 2023. 


Questions are permitted beyond the Question Due-Date; however, Leidos Biomedical Research cannot guarantee a response will be provided.

Connor Cigrang

In accordance with the Leidos Biomedical Research Solicitation/RFP S23-093, article E.2., a Pre-Offer Submission Teleconference will be held on October 12, 2023. The meeting time for the Teleconference shall be 1:00 – 2:00PM (Eastern Standard Time).  Those who wish to participate shall contact the cognizant Subcontracts Administrators (Connor Cigrang at and Josh Wynne at to receive the meeting call-in details.