Research Associate III, Next Generation Sequencing (req2185)

Posted: 10/8/2021
Location: Frederick, MD
Employee Type: exempt full-time
Job ID: req2185


The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR), where CRTP scientists work collaboratively with intramural NCI investigators to provide research technologies and expertise.


  • The Sequencing Facility is a high throughput laboratory providing cutting edge next generation technologies to the National Cancer Institute. Current platforms include the Illumina NovaSeq, NextSeq, MiSeq, PacBio and additional platforms in the future. All projects are of a highly specialized nature and require technical proficiency, problem solving skills and good judgment
  • The Research Associate III will be responsible for assisting with next generation (NGS) sequencing for the core facility. Responsible for all ongoing daily activities including library prep and sequencer set up, maintenance of equipment, use of protocols, sample quality control and troubleshooting of problems with direct coordination of the supervisor
  • Project support for multiple investigators, including involvement in initial project discussion, library preparation, quality control and sequencing
  • Contributing to consultations on experimental design, sample preparation, technical expertise, and project troubleshooting
  • Responsible for overseeing and leading projects from planning through to completion
  • Requires adherence to strict safety protocols and may require the use of personal protective equipment


To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

  • Possession of Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirement, a minimum of 8 years of related experience
  • Strong background in cell and molecular biology
  • Knowledge of or experience with next generation sequencing methods
  • Ability to obtain and maintain a security clearance


Candidates with these desired skills will be given preferential consideration:

  • Hands-on experience with next-gen library preparation and sequencing
  • Experience working in a core facility or other team-based environment
  • Demonstrated ability to learn new technologies quickly and ability to assist in new protocol development
  • Familiarity with diverse sample types and processing methods
  • Must have excellent written and verbal communication skills
  • Must be detail-oriented, and able to manage multiple projects simultaneously


  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations