Dr. Yvonne A. Evrard is the Operations and Program Manager for the NCI Patient-Derived Models Repository (PDMR, pdmr.cancer.gov) in support of the Division of Cancer Treatment and Diagnosis (DCTD, NCI). She provides scientific oversite for model development, characterization, and preclinical modeling efforts for the PDMR. The PDMR is focused on obtaining clinical specimens from cancers that are underrepresented in the PDX community, including rare cancers, such that researchers can perform adequately powered preclinical studies for biomarker and therapeutic discovery.
Dr. Evrard oversees multiple funding opportunities for acquisition of patient tumor material for model development as well as deposition of patient-derived models from outside researchers into the PDMR. She oversees daily operations of the PDMR and coordinates the efforts of the interdisciplinary teams that are needed to characterize these models for distribution to academic and commercial researchers.
She earned a Ph.D. in Biochemistry and Molecular Biology from The University of Texas Health Science Center at Houston, Graduate School of Biomedical Sciences and has a research background in developmental biology, generation of transgenic mouse models, chromatin biology, and molecular biology.
