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Valuable medical and biological images languish for want of support
More countries should invest in open data resources, or an immense amount of valuable data will languish, a team of concerned scientists recommended in a Nature Methods opinion column.
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Different high-risk HPV infections don’t spur cancers at the same rate
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KRAS G12C
RAS drug discovery at Frederick National Laboratory reaches lung cancer patients in a clinical trial
A first-in-human study seeks to determine the drug’s safety and tolerability and to detect potential antitumor activity.
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Did you know?
About 30% of all human cancers are driven by mutations of the RAS family of genes. The RAS Initiative endeavors to better understand the RAS oncogene and discover its vulnerabilities to treat RAS-related cancers.
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Within FNL, innovation plays a pivotal role in delivering new and enhanced technologies that empower us to tackle essential scientific inquiries, enhance our services, and ultimately contribute to the wellbeing of patients.
Vladimir Popov, Ph.D., MBA
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BBO-10203
Drug blocking cancer-driving RAS-PI3K pathway enters clinical trials
Second drug candidate targeting RAS-related cancers developed by the RAS Initiative, BridgeBio Oncology Therapeutics and Lawrence Livermore National Laboratory.
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Barcode Analysis Tool
Download files to demultiplex next-generation sequencing and determine the abundance of individually barcoded SIV/SHIV viral lineages.
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Assay Cascade Characterization Program
Next deadline to apply: Sept. 2, 2025
Preclinical characterization of nanoparticles to facilitate the regulatory review of nanotechnology concepts intended as cancer therapies and diagnostics.
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Register now
Apr 9, 2025
Driving results through crisis and uncertainty: From Operation Warp Speed to the World
Col. Matt Clark as he covers leader and followership principles and competencies.
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Quantitative assessment of HIV or SIV viral DNA in laser capture microdissected immune cells
Viral Integration Site Analysis (VISA) for HIV studies
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Assessment of Drug Efficacy in a Survival Study
In Vitro
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Pharmacokinetic Evaluation in Kras/p53 PDAC Mice
Time Course Assessment of Tumor Response to Therapeutics
Tolerance Evaluation of Experimental Compound in Kras/p53 PDAC Mice
Use of Mouse Embryonic Stem Cells Expressing miRNAs
Nanomedicine & Nanoformulation
An
in vitro
drug release study in human plasma
Pharmacokinetic study of nanomedicine in rats
Other
Detection of Mycobacterium tuberculosis DNA
Did you know?
We are home to unique scientific expertise and technological capabilities available nowhere else. The Technical Services Program through the Partnership Development Office makes some of these capabilities and services readily available to the external research community at-cost to advance biomedical research around the world.
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Collection of scientific groups at FNL working to develop, deposit and share standards and references in biological research.
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SeroNet study samples available to request
Investigators can request serological samples from SARS-CoV-2 studies through the SeroNet Study Collections.
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National laboratories’ publication wins best paper award
A review authored by a team spanning LLNL and FNL has been awarded one of two recent Best Paper designations among papers published in Current Opinion in Structural Biology.
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More countries should invest in open data resources, or an immense amount of valuable data will languish, a team of concerned scientists recommended in a Nature Methods opinion column.
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What do you enjoy about working at the Frederick National Laboratory?
I enjoy coming to work every day because of the wonderful team we have.
Chris Karlovich, Ph.D.
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Did you know?
To date, the Antibody Characterization Laboratory has developed 947 antibodies to 571 antigen targets.
Rachana Agarwal
Director
,
Biospecimen Research Group
Research
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AIDS and Cancer Virus Program
Sections
Retroviral Evolution Section
Retroviral Pathogenesis Section
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Molecular Immunology Section
Bioinformatics and Computational Science
Advanced Biomedical Computational Science
Center for Technical Operations Support
Cancer Research Technology Program
Advanced Cryo-Electron Microscopy Technology Group
Antibody Characterization Laboratory
Cancer Data Science Initiatives
CLIA Molecular Diagnostics Laboratory
Imaging Mass Cytometry Laboratory
Protein Expression Laboratory
Laboratory Animal Sciences Program
Animal Diagnostics Laboratory
Animal Research Technical Support
Center for Advanced Preclinical Research
Genome Modification Core
Gnotobiotics Facility
Laboratory Animal Medicine
Molecular Histopathology Laboratory
Mouse Modeling and Cryopreservation
Small Animal Imaging Program
Vaccine, Immunity, and Cancer Directorate
Cancer Immunoprevention Laboratory
Center of Excellence for Serology Development and Emergency Preparedness
HPV and COVID-19 Serology Laboratories
SeroNet Coordinating Center
Clinical Trial Support
Applied and Developmental Research Directorate
Clinical Services Program
AIDS Monitoring Laboratory
Bioprocessing Laboratory
Blood Processing Core
Clinical Support Laboratory
Flow Cytometry Support Laboratory
Immunological Monitoring Laboratory
Laboratory of Human Retrovirology and Immunoinformatics
Laboratory of Molecular Cell Biology
Neutrophil Monitoring Laboratory
Radiochemistry Program
Virus Isolation and Serology Laboratory
DCTD Support
Cancer Imaging Informatics Laboratory
Clinical Pharmacodynamics - Biomarkers Program
In Vitro Evaluation and Molecular Pharmacology Laboratories
In Vivo Evaluation Program
Investigative Toxicology Laboratory
NExT Chemical Biology Consortium Support Programs
Natural Products Support Group
Pharmacokinetics and Drug Analysis Group
Radiochemistry Support Group
Biopharmaceutical Development Program
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Service & Maintenance Agreement for Environmental Test Chambers
Service & Maintenance Agreement for Microbial Detection System
Service Maintenance Agreement for De-Rouging, Passivation, Cleaning of WFI & Clean Steam Systems
Stable Clone Production for Anti-CD6 Monoclonal Antibodies
Stable Clone Production for Anti-CD6 Monoclonal Antibodies
