Offering current 3D optical (confocal and super-resolution) microscopy for imaging
of living and fixed cells and tissues; computational resources for visualization;
and extraction of quantitative information from images. The program focuses its
research and development activities to quantitatively understanding the molecular
basis of three-dimensional (3D) cell organization, motility, invasion, and differentiation
using live, 3D tissue culture models.
Confocal Microscopy Capabilities: The program ensures that researchers
have advanced technology and in-depth expertise in microscopy and related areas.
The Confocal Microscopy Facility delivers current 3D optical (confocal and super-resolution)
microscopy for imaging of living and fixed cells and tissues; computational resources
for visualization and extraction of quantitative information from images.
Providing Electron Microscopy capabilities to the NIH biomedical research community
with rapid turnaround time and the highest quality image data. Unique expertise
and EM technologies to assist our investigators explore new avenues of research
in order to enhance the knowledge of biological systems.
Technical Capabilities: The program provides Transmission Electron
Microscopy (TEM) and Scanning Electron Microscopy (SEM) techniques as well as expertise
in the following specialized areas:
Instrumentation: The laboratory includes four transmission electron
microscopes and one scanning electron microscope. These scopes are supported by
an FEI Vitrobot, four ultramicrotomes, a high resolution sputter coater and light
microscopes with digital capture capability.
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