Working with the BDP

The Frederick National Laboratory for Cancer Research (FNLCR) is a Federally Funded Research and Development Center (FFRDC) operated by Leidos Biomedical Research Inc., under prime contract with the National Cancer Institute (NCI). As part of the Frederick National Laboratory for Cancer Research, the BDP also works under collaborative agreements with other government agencies, universities, and industry, including national and international companies. The goal of the program is to move promising treatments for cancer, AIDS, and infectious diseases into clinical trials.

Opportunities for collaboration are reviewed and approved by NCI. Collaborators include academia, industry, and other government agencies. BDP contractor staff provides their unique expertise and works with collaborators to develop a manufacturing process suitable for its intended purpose, whether that is pre-clinical animal studies or early-phase clinical trials. Project teams, consisting of representatives from the collaborator/principal investigator, NCI, and BDP, manage projects from inception to completion. The project team addresses challenges in real time and completes projects in a milestone-based approach.

The BDP is experienced in the transfer of manufacturing and testing methods developed to support pharma and government programs that own the licensed product rights for commercialization. As part of this activity, the BDP’s state-of-the-art facility (operated by Leidos Biomedical Research, Inc., for NCI) has laboratory space available for collaborators to work alongside BDP contractor employees to develop and learn production and purification techniques, and testing methods. The BDP also provides opportunities for guest researchers interested in the development of novel biopharmaceuticals.

Government and Non-Government Sources for Funding

  • NCI’s Experimental Therapeutics (NExT) Program
  • NCI Intramural Research Community
  • Interagency agreements between federal agencies and NCI such as:
    • National Institute for Allergy and Infectious Diseases (NIAID)
    • Department of Defense
    • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    • National Center for Advancing Translational Sciences (NCATS)
  • Cooperative Research and Development Agreements with companies and universities by Leidos Biomed (cCRADA’s) or NCI (CRADA’s)