Paving the Way for Biomedical Innovation

The Frederick National Laboratory meets the nation’s most urgent biomedical research needs and serves as a national and global resource for the scientific community. 

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Reproducibility symposium met ‘highest expectations,’ laid plans for more robust science

Reproducibility in Science Symposium brought interdisciplinary crowd together to discuss elevating standards to strengthen...
Cancer Research

Genetic classification of cervical cancer leads to experimental targeted treatment

Scientists have found a new way to sort cervical tumors by their DNA, leading to more precise, personalized treatment options...

Analysis of paired blood biopsies, tumor tissue as biomarkers for cancer to be presented at ASCO

FNL scientists will present a recent study comparing mutations found in paired tuors and ctDNA at the 2026 American Society...

New tools may better predict breast cancer in women of African descent

Researchers developed new polygenic risk factor models built around four especially aggressive breast cancer phenotypes.

Researchers identify lower GI tract tissues as source of initial rebound of HIV-like virus after stopping ART

A new study used an innovative method to track anatomic origin of rebound of HIV-like virus.

Symposium: Upcoming Life Sciences Symposium will grapple with reproducibility crisis

Experts across scientific fields will convene June 16–18 for a symposium aiming to ameliorate the so-called “reproducibility...

NIH partnership establishes new Gene Therapy Immunology and Standards Laboratory

A new initiative aims to standardize gene therapy research, speeding the path to clinical trials and new treatments.
What is this?

Atomic contours visible in cryo-Electron Microscopy map of the human ribosome. The Advanced Cryo-Electron Microscopy Technology Group explores emerging imaging platforms and develops methodologies, focusing on projects with the potential to make cryo-EM a more widely accessible technique. The group works with the National Cryo-Electron Microscopy Facility, which provides extramural cancer researchers access to the latest technology for high-resolution imaging.
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Initiative

RAS Initiative

Discovering the Secrets of a Prevalent Oncogene
The RAS Initiative mobilizes the cancer research community to develop ways to treat cancers driven by the mutant RAS gene in an open model of collaboration among government, academic, and industry researchers.
Discover RAS Science
220,000
People per year in the U.S. are diagnosed with cancers caused by KRAS mutations.
What is this? Surface representation of the structure of an oncogenic mutant of KRAS in complex with RAS-binding domains of RAF1 Kinase. The GMPPNP bound to oncogenic KRAS mutant is shown in ball-and-stick representation.
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Center for Innovation and Strategic Partnerships

Cultivating innovation through technology development and partnerships
We bring the Frederick National Laboratory’s distinct capabilities to the broader research community to help solve urgent problems in biomedical research.
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156
Cooperative Research and Development Agreements and CRADA amendments to enable and extend research projects between FNL scientists and external investigators.

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Work with the best of the best biomedical researchers and investigators. Be a part of groundbreaking solutions that benefit public health throughout the world. And, enjoy some of the best benefits in the region. We are looking for smart, passionate problem solvers for benchwork, data science, manufacturing, and more.

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