Paving the Way for Biomedical Innovation

The Frederick National Laboratory meets the nation’s most urgent biomedical research needs and serves as a national and global resource for the scientific community. 

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Uncommon testing capability supports CDC investigation into KSHV-infected organ transplants

Viral Oncology Section’s specialized testing capability supports CDC investigation into rise in Kaposi sarcoma disease in...

Team cuts one to two-year vaccine production timeline to fewer than 100 days

Vaccine Clinical Materials Program developed a new workflow to produce ready-for-testing vaccines in 13 weeks rather than the...

Reproducibility symposium met ‘highest expectations,’ laid plans for more robust science

Reproducibility in Science Symposium brought interdisciplinary crowd together to discuss elevating standards to strengthen...
Cancer Research

Genetic classification of cervical cancer leads to experimental targeted treatment

Scientists have found a new way to sort cervical tumors by their DNA, leading to more precise, personalized treatment options...

Analysis of paired blood biopsies, tumor tissue as biomarkers for cancer to be presented at ASCO

FNL scientists will present a recent study comparing mutations found in paired tuors and ctDNA at the 2026 American Society...

New tools may better predict breast cancer in women of African descent

Researchers developed new polygenic risk factor models built around four especially aggressive breast cancer phenotypes.

Researchers identify lower GI tract tissues as source of initial rebound of HIV-like virus after stopping ART

A new study used an innovative method to track anatomic origin of rebound of HIV-like virus.
What is this?

Atomic contours visible in cryo-Electron Microscopy map of the human ribosome. The Advanced Cryo-Electron Microscopy Technology Group explores emerging imaging platforms and develops methodologies, focusing on projects with the potential to make cryo-EM a more widely accessible technique. The group works with the National Cryo-Electron Microscopy Facility, which provides extramural cancer researchers access to the latest technology for high-resolution imaging.
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08/27 @ 8:00amATRF Emerging Immunotherapeutic Strategies for an HIV Functional… 09/09 @ 11:30amATRF 2026 Technology Showcase
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Initiative

Scientific Standards Hub

Bridging gaps in scientific reproducibility
Our scientists establish standards and reference reagents for diverse scientific  disciplines and  encourage the adoption of benchmarks  among researchers. 
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8
disciplines with tools to help bridge gaps in scientific reproducibility.
Initiative

RAS Initiative

Discovering the Secrets of a Prevalent Oncogene
The RAS Initiative mobilizes the cancer research community to develop ways to treat cancers driven by the mutant RAS gene in an open model of collaboration among government, academic, and industry researchers.
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220,000
People per year in the U.S. are diagnosed with cancers caused by KRAS mutations.
What is this? Surface representation of the structure of an oncogenic mutant of KRAS in complex with RAS-binding domains of RAF1 Kinase. The GMPPNP bound to oncogenic KRAS mutant is shown in ball-and-stick representation.
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Work with the best of the best biomedical researchers and investigators. Be a part of groundbreaking solutions that benefit public health throughout the world. And, enjoy some of the best benefits in the region. We are looking for smart, passionate problem solvers for benchwork, data science, manufacturing, and more.

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